2. Vitamin D Related/Nuclear Receptor
  3. VD/VDR
  4. MC 1046

MC 1046  (Synonyms: Impurity A of Calcipotriol)

Cat. No.: HY-15264 Purity: 91.48%
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MC 1046(Impurity A of Calcipotriol) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors.

For research use only. We do not sell to patients.

MC 1046 Chemical Structure

MC 1046 Chemical Structure

CAS No. : 126860-83-1

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1 mg USD 500 In-stock
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Based on 1 publication(s) in Google Scholar

MC 1046 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE MC 1046

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

MC 1046(Impurity A of Calcipotriol) is an impurity of Calcipotriol; Calcipotriol (MC 903; Calcipotriene) is a ligand of VDR-like receptors. IC50 value: Target: Vitamin D3 analog that displays minimal effects on calcium homeostasis. Regulates cell differentiation and proliferation; Calcipotriol (MC 903; Calcipotriene) exhibits antiproliferative activity against human HL-60, HL60/MX2, MCF-7, T47D, SCC-25 and mouse WEHI-3 cancer cell lines.

Molecular Weight

410.59

Formula

C27H38O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C[C@]1(CCC/2)C(C2=C\C=C3C[C@@H](O)C[C@H](O)C\3=C)CC[C@@H]1[C@H](C)/C=C/C(C4CC4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (121.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4355 mL 12.1776 mL 24.3552 mL
5 mM 0.4871 mL 2.4355 mL 4.8710 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4355 mL 12.1776 mL 24.3552 mL 60.8880 mL
5 mM 0.4871 mL 2.4355 mL 4.8710 mL 12.1776 mL
10 mM 0.2436 mL 1.2178 mL 2.4355 mL 6.0888 mL
15 mM 0.1624 mL 0.8118 mL 1.6237 mL 4.0592 mL
20 mM 0.1218 mL 0.6089 mL 1.2178 mL 3.0444 mL
25 mM 0.0974 mL 0.4871 mL 0.9742 mL 2.4355 mL
30 mM 0.0812 mL 0.4059 mL 0.8118 mL 2.0296 mL
40 mM 0.0609 mL 0.3044 mL 0.6089 mL 1.5222 mL
50 mM 0.0487 mL 0.2436 mL 0.4871 mL 1.2178 mL
60 mM 0.0406 mL 0.2030 mL 0.4059 mL 1.0148 mL
80 mM 0.0304 mL 0.1522 mL 0.3044 mL 0.7611 mL
100 mM 0.0244 mL 0.1218 mL 0.2436 mL 0.6089 mL
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MC 1046 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MC 1046126860-83-1Impurity A of CalcipotriolMC1046MC-1046VD/VDRVitamin DVitamin D receptorInhibitorinhibitorinhibit

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