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(Synonyms BYL 719; BYL719)
BYL-719 Technical Data:
Price and Availability of BYL-719
BYL-719 M.Wt: 441.47
BYL-719 Formula: C19H22F3N5O2S
Please store the product under the recommended conditions in
Certificate of Analysis.
BYL-719 CAS No.: 1217486-61-7
BYL-719 Solubility: DMSO
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BYL-719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL-719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.