1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Tolazoline

Tolazoline(Imidaline) is a non-selective competitive α-adrenergic receptor antagonist.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Tolazoline hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Tolazoline Chemical Structure

Tolazoline Chemical Structure

CAS No. : 59-98-3

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Description

Tolazoline(Imidaline) is a non-selective competitive α-adrenergic receptor antagonist.

IC50 & Target

α-adrenoceptor.

In Vitro

Tolazoline (Imidaline) can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product. The structure of Tolazoline (Imidaline) is strikingly similar to α-adrenergic agonists, which are antiedema sympathomimetics.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

160.22

Formula

C10H12N2

CAS No.
SMILES

C1(CC2=CC=CC=C2)=NCCN1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Tolazoline Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Tolazoline
Cat. No.:
HY-A0066
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