(±)-Befunolol

Cat. No.: HY-101752: FAQs
Data Sheet Handling Instructions

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(±)-Befunolol is a β-adrenoceptor blocking agent.

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(±)-Befunolol Chemical Structure

CAS No. : 39552-01-7

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1 Publications Citing Use of MCE (±)-Befunolol

•J Pharmaceut Biomed. 2020, 113870.

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Description	(±)-Befunolol is a β-adrenoceptor blocking agent.
IC₅₀ & Target	Adrenoreceptor^[1]
In Vitro	A β-adrenoceptor blocking agent, Befunolol, is found to has intrinsic sympathomimetic activities in isolated right atria, trachea and taenia caecum of guinea pig (intrinsic activities are 0.22-0.28). The pD2-values of Befunolol estimated in the isolated organs are significantly different from its pA2-values against isoprenaline. Befunolol interacts with the beta-adrenoceptor where there may be two different sites: one site for agonistic action and the other for competitive antagonistic action. The intrinsic activity of Befunolol may be equal to its selectivity for both the sites^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. (±)-Befunolol Related Antibodies
Molecular Weight	291.34
Formula	C₁₆H₂₁NO₄
CAS No.	39552-01-7
SMILES	CC(C1=CC2=CC=CC(OCC(O)CNC(C)C)=C2O1)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Takayanagi I, et al. A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs. Gen Pharmacol. 1985;16(3):265-7. [Content Brief]

(±)-Befunolol Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(±)-Befunolol39552-01-7Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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(±)-Befunolol

(±)-Befunolol Related Antibodies