[5-(2-Thienyl)-3-isoxazolyl]methanol

Cat. No.: HY-W029719 Purity: 99.77%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

[5-(2-Thienyl)-3-isoxazolyl]methanol (Compound D) is an AgrA-DNA binding inhibitor. [5-(2-Thienyl)-3-isoxazolyl]methanol can be used for S.aureus infection research.

For research use only. We do not sell to patients.

[5-(2-Thienyl)-3-isoxazolyl]methanol Chemical Structure

CAS No. : 194491-44-6

Size	Price	Stock	Quantity
Oil + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 33	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 33	In-stock	Estimated Time of Arrival: December 31
Oil
50 mg	USD 30	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 160	In-stock	Estimated Time of Arrival: December 31
1 g	USD 256	In-stock	Estimated Time of Arrival: December 31
5 g		Get quote
10 g		Get quote

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Biological Activity
Purity & Documentation
References
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Description

[5-(2-Thienyl)-3-isoxazolyl]methanol (Compound D) is an AgrA-DNA binding inhibitor. [5-(2-Thienyl)-3-isoxazolyl]methanol can be used for S.aureus infection research^[1].

Molecular Weight

181.21

Formula

C₈H₇NO₂S

CAS No.

194491-44-6

Appearance

Oil

Color

Light yellow to brown

SMILES

OCC1=NOC(C2=CC=CS2)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (551.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5185 mL	27.5923 mL	55.1846 mL
5 mM	1.1037 mL	5.5185 mL	11.0369 mL
10 mM	0.5518 mL	2.7592 mL	5.5185 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.77%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (248 KB) HNMR (400 KB) LCMS (121 KB)

Handling Instructions (2659 KB)

References

[1]. Leonard PG, et al. Identification of a hydrophobic cleft in the LytTR domain of AgrA as a locus for small molecule interactions that inhibit DNA binding. Biochemistry. 2012 Dec 18;51(50):10035-43. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.5185 mL	27.5923 mL	55.1846 mL	137.9615 mL
	5 mM	1.1037 mL	5.5185 mL	11.0369 mL	27.5923 mL
	10 mM	0.5518 mL	2.7592 mL	5.5185 mL	13.7961 mL
	15 mM	0.3679 mL	1.8395 mL	3.6790 mL	9.1974 mL
	20 mM	0.2759 mL	1.3796 mL	2.7592 mL	6.8981 mL
	25 mM	0.2207 mL	1.1037 mL	2.2074 mL	5.5185 mL
	30 mM	0.1839 mL	0.9197 mL	1.8395 mL	4.5987 mL
	40 mM	0.1380 mL	0.6898 mL	1.3796 mL	3.4490 mL
	50 mM	0.1104 mL	0.5518 mL	1.1037 mL	2.7592 mL
	60 mM	0.0920 mL	0.4599 mL	0.9197 mL	2.2994 mL
	80 mM	0.0690 mL	0.3449 mL	0.6898 mL	1.7245 mL
	100 mM	0.0552 mL	0.2759 mL	0.5518 mL	1.3796 mL