1. Neuronal Signaling
  2. Monoamine Oxidase
  3. Iproniazid phosphate

Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity.

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Iproniazid phosphate Chemical Structure

Iproniazid phosphate Chemical Structure

CAS No. : 305-33-9

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Solid + Solvent
10 mM * 1 mL in DMSO
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100 mg USD 60 In-stock
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Based on 2 publication(s) in Google Scholar

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Description

Iproniazid phosphate is a non-selective, irreversible monoamine oxidase (MAO) inhibitor of the hydrazine class. Iproniazid phosphate has antidepressive activity[1].

Molecular Weight

277.21

Formula

C9H16N3O5P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=NC=C1)NNC(C)C.O=P(O)(O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (360.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (180.37 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6074 mL 18.0369 mL 36.0737 mL
5 mM 0.7215 mL 3.6074 mL 7.2147 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.92%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.6074 mL 18.0369 mL 36.0737 mL 90.1843 mL
5 mM 0.7215 mL 3.6074 mL 7.2147 mL 18.0369 mL
10 mM 0.3607 mL 1.8037 mL 3.6074 mL 9.0184 mL
15 mM 0.2405 mL 1.2025 mL 2.4049 mL 6.0123 mL
20 mM 0.1804 mL 0.9018 mL 1.8037 mL 4.5092 mL
25 mM 0.1443 mL 0.7215 mL 1.4429 mL 3.6074 mL
30 mM 0.1202 mL 0.6012 mL 1.2025 mL 3.0061 mL
40 mM 0.0902 mL 0.4509 mL 0.9018 mL 2.2546 mL
50 mM 0.0721 mL 0.3607 mL 0.7215 mL 1.8037 mL
60 mM 0.0601 mL 0.3006 mL 0.6012 mL 1.5031 mL
80 mM 0.0451 mL 0.2255 mL 0.4509 mL 1.1273 mL
100 mM 0.0361 mL 0.1804 mL 0.3607 mL 0.9018 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Iproniazid phosphate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Iproniazid phosphate
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