1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Ornithine

L-Ornithine  (Synonyms: (S)-2,5-Diaminopentanoic acid)

Cat. No.: HY-B1352 Assay: 99.56%
COA Handling Instructions

L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective.

For research use only. We do not sell to patients.

L-Ornithine Chemical Structure

L-Ornithine Chemical Structure

CAS No. : 70-26-8

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
100 mg USD 50 In-stock
500 mg USD 75 In-stock
1 g   Get quote  
5 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of L-Ornithine:

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Microbial Metabolite

 

In Vitro

L-Ornithine (0-10 mM) activates the CaSR in a concentration-dependent manner and exerts effects on Ca2+ signaling in HK-2 cells[2].
L-Ornithine (10 mM) activates TRPC channels mediated Ca2+ entry pathway in HK-2 cells[2].
L-Ornithine (100 or 300 μM; 24 h) shows the protection against ROS generation in HK-2 cells via ROCE pathway[2].
L-Ornithine (10 μM) can protect the ROS and oxidative damage in HK-2 cells exposed to H2O2[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

132.16

Formula

C5H12N2O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N[C@@H](CCCN)C(O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (378.33 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.5666 mL 37.8329 mL 75.6659 mL
5 mM 1.5133 mL 7.5666 mL 15.1332 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.56%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 7.5666 mL 37.8329 mL 75.6659 mL 189.1646 mL
5 mM 1.5133 mL 7.5666 mL 15.1332 mL 37.8329 mL
10 mM 0.7567 mL 3.7833 mL 7.5666 mL 18.9165 mL
15 mM 0.5044 mL 2.5222 mL 5.0444 mL 12.6110 mL
20 mM 0.3783 mL 1.8916 mL 3.7833 mL 9.4582 mL
25 mM 0.3027 mL 1.5133 mL 3.0266 mL 7.5666 mL
30 mM 0.2522 mL 1.2611 mL 2.5222 mL 6.3055 mL
40 mM 0.1892 mL 0.9458 mL 1.8916 mL 4.7291 mL
50 mM 0.1513 mL 0.7567 mL 1.5133 mL 3.7833 mL
60 mM 0.1261 mL 0.6305 mL 1.2611 mL 3.1527 mL
80 mM 0.0946 mL 0.4729 mL 0.9458 mL 2.3646 mL
100 mM 0.0757 mL 0.3783 mL 0.7567 mL 1.8916 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Ornithine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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