1. GPCR/G Protein
  2. Angiotensin Receptor
  3. Losartan-d4

Losartan-d4  (Synonyms: DuP-753 d4)

Cat. No.: HY-17512S Purity: ≥99.0%
COA Handling Instructions

Losartan-d4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

For research use only. We do not sell to patients.

Losartan-d<sub>4</sub> Chemical Structure

Losartan-d4 Chemical Structure

CAS No. : 1030937-27-9

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Based on 1 publication(s) in Google Scholar

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Description

Losartan-d4 is the deuterium labeled Losartan. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.

IC50 & Target

AT1 Receptor

 

Molecular Weight

426.94

Formula

C22H19D4ClN6O

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC1=C(Cl)N=C(CCCC)N1CC2=C([2H])C([2H])=C(C3=CC=CC=C3C4=NNN=N4)C([2H])=C2[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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Losartan-d4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Losartan-d4
Cat. No.:
HY-17512S
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