2. Signaling Pathways
  3. Immunology/Inflammation
  4. IRAK
  5. IRAK Isoform
  6. IRAK Degrader

IRAK Degrader

IRAK Degraders (2):

Cat. No. Product Name Effect Purity
  • HY-148290
    KTX-951
    		Degrader 98.03%
    KTX-951 is a PROTAC targeting IRAK4 degradation (DC50=18 nM). KTX-951 (10 mg/kg) shows the oral bioavailability (F%) of 22% in a rat model. KTX-951 has good anticancer potential.
  • HY-153368
    IRAK degrader-1
    		Degrader
    IRAK degrader-1 (example I-3) is a potent IRAK degrader.