2. Signaling Pathways
  3. Stem Cell/Wnt
    TGF-beta/Smad
  4. PKA
  5. PKA Agonist

PKA Agonist

PKA Agonists (2):

Cat. No. Product Name Effect Purity
  • HY-110218
    CW 008
    		Agonist 98.15%
    CW 008, a derivative of pyrazole-pyridine, is a CREB or PKA pathway agonist. CW 008 also is a stem cell differentiating agent. CW 008 stimulates osteoblast differentiation of human MSCs and increases bone formation in ovariectomized mice. CW008 promotes osteogenesis by activating cAMP/PKA/CREB signaling pathway and inhibiting leptin secretion.
  • HY-137640A
    Sp-8-Br-cAMPS sodium
    		Agonist
    Sp-8-Br-cAMPS sodium is a cAMP analog, which performs a protein kinase A (PKA) activating activity with EC50 of 360 nM. Sp-8-Br-cAMPS sodium inhibits proliferation of T cells and the haemocyte non-self response in Lepidoptera larve.