2. Signaling Pathways
  3. Anti-infection
  4. SARS-CoV
  5. SARS-CoV Degrader

SARS-CoV Degrader

SARS-CoV Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-157805
    PROTAC SARS-CoV-2 Mpro degrader-2
    		Degrader
    PROTAC SARS-CoV-2 Mpro degrader-2 (Compound 6) is a potent PROTAC degrader of SARS-CoV-2 Mpro. PROTAC SARS-CoV-2 Mpro degrader-2 has broad-spectrum antiviral activity against CoVs, including SARS-CoV-2 (EC50 = 10.8 μM), HCoV-OC43 (EC50 = 1.6 μM) and HCoV-229E (EC50 = 6.5 μM). PROTAC SARS-CoV-2 Mpro degrader-2 exhibits potent activity against SARS-CoV-2 in Calu-3 cells, with an EC50 of 0.89 μM.