2. Signaling Pathways
  3. Apoptosis
  4. c-Myc
  5. c-Myc Degrader

c-Myc Degrader

c-Myc Degraders (4):

Cat. No. Product Name Effect Purity
  • HY-162318
    MYC degrader 1
    		Degrader
    A80.2HCl is a MYC degrader that restores pRB1 protein activity and reduces MYC-dependent CDK4/6 resistance. A80.2HCl has antitumor activity.
  • HY-153713
    MYC-RIBOTAC
    		Degrader 98.05%
    MYC-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) to MYC internal ribosome entry site (IRES).MYC-RIBOTAC contains a MYC mRNA-binder and a small molecule that recruits and locally activates RNase L1 and decreases the mRNA and protein expression levels of MYC, induces apoptosis. MYC-RIBOTAC can be used for anticancer research.
  • HY-162318A
    MYC degrader 1 TFA
    		Degrader
    MYC degrader 1 TFA is a MYC degrader that restores pRB1 protein activity and reduces MYC-dependent CDK4/6 resistance. MYC degrader 1 TFA has antitumor activity.
  • HY-150259
    MDEG-541
    		Degrader
    MDEG-541 is a potent MYC-MAX degrader. MDEG-541 is a PROTAC that based on the MYC-MAX dimerization inhibitor 10058-F4 derivative 28RH and Thalidomide (HY-14658). MDEG-541 shows antiproliferative activity. MDEG-541 decreases the expression of GSPT1, MYC, GSPT2, PLK1 protein.