2. Signaling Pathways
  3. Epigenetics
  4. METTL3

METTL3

Methyltransferase-like 3

 

METTL3 Related Products (10):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-115717
    UZH2
    		Inhibitor 98.73%
    UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.
    UZH2
  • HY-156677
    STC-15
    		Inhibitor 99.36%
    STC-15 (example 70) is an orally active METTL3 inhibitor used in the study of proliferative diseases such as cancer and autoimmune diseases.
    STC-15
  • HY-153625
    STM2120
    		Inhibitor 99.92%
    STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM.
    STM2120
  • HY-134673B
    UZH1b
    		Inhibitor 99.75%
    UZH1b is an enantiomer of UZH1a (a METTL3 inhibitor). UZH1b is essentially inactive for METTL3 (IC50=28 µM).
    UZH1b
  • HY-148467
    METTL3-IN-1
    		Inhibitor
    METTL3-IN-1 (compound 23) is a polyheterocyclic compound, acts as METTL3 inhibitor.
    METTL3-IN-1
  • HY-162080
    METTL1-WDR4-IN-1
    		Inhibitor
    METTL1-WDR4-IN-1 (1) is a METTL1-WDR4 inhibitor, with an IC50 of 144 μM.
    METTL1-WDR4-IN-1
  • HY-148468
    METTL3-IN-2
    		Inhibitor
    METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells.
    METTL3-IN-2
  • HY-148469
    METTL3-IN-3
    		Inhibitor
    METTL3-IN-3 (compound 11) is a polyheterocyclic compound, acts as METTL3 inhibitor.
    METTL3-IN-3
  • HY-156759
    METTL3-IN-5
    		Inhibitor
    METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research.
    METTL3-IN-5
  • HY-154997
    7OQL
    		Inhibitor
    7OQL (compound 54) is a selective METTL3 inhibitor (IC50=0.054 µM). 7OQL has the potential to be used in the study of cancer.
    7OQL