2. Trimethoprim 3-oxide

Trimethoprim 3-oxide  (Synonyms: Trimethoprim 3-N-oxide)

Cat. No.: HY-100645
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Triméthoprime 3-oxyde (Triméthoprime 3-N-oxyde) est le principal métabolite du triméthoprime.

Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim.

For research use only. We do not sell to patients.

Trimethoprim 3-oxide Chemical Structure

Trimethoprim 3-oxide Chemical Structure

CAS No. : 27653-67-4

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Trimethoprim 3-oxide Related Antibodies

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Description

Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) is the primary metabolite of trimethoprim[1].

In Vitro

Trimethoprim 3-oxide is the primary metabolite of trimethoprim[1].
Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Trimethoprim 3-oxide Related Antibodies
Molecular Weight

306.32

Formula

C14H18N4O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NC1=NC=C(CC2=CC(OC)=C(OC)C(OC)=C2)C(N)=[N+]1[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trimethoprim 3-oxide27653-67-4Trimethoprim 3-N-oxideInhibitorinhibitorinhibit

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