1. Neuronal Signaling
  2. Cholinesterase (ChE) Amyloid-β
  3. AChE/Aβ-IN-4

AChE/Aβ-IN-4 is a dual inhibitor of acetylcholinesterase (AChE) and β-amyloid (Aβ) aggregation, with the IC50 values of 1.72 ± 0.18 μM and 1.42 ± 0.3 μM, respectively. AChE/Aβ-IN-4 plays an impotant role in neurological disorders, such as Alzheimer’s disease.

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AChE/Aβ-IN-4 Chemical Structure

AChE/Aβ-IN-4 Chemical Structure

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Description

AChE/Aβ-IN-4 is a dual inhibitor of acetylcholinesterase (AChE) and β-amyloid (Aβ) aggregation, with the IC50 values of 1.72 ± 0.18 μM and 1.42 ± 0.3 μM, respectively. AChE/Aβ-IN-4 plays an impotant role in neurological disorders, such as Alzheimer’s disease[1].

IC50 & Target

AChE

1.72 ± 0.1 μM (IC50)

Molecular Weight

390.48

Formula

C23H26N4O2

SMILES

O=C(NC1=CC=C(C)C=C1)CN2CCN(C3=CC(NC4=C3C=C(C)C=C4)=O)CC2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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AChE/Aβ-IN-4 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AChE/Aβ-IN-4
Cat. No.:
HY-157441
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