2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adenylosuccinic acid

Adenylosuccinic acid  (Synonyms: Adenylosuccinate; Aspartyl adenylate)

Cat. No.: HY-127137
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Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD).

For research use only. We do not sell to patients.

Adenylosuccinic acid Chemical Structure

Adenylosuccinic acid Chemical Structure

CAS No. : 19046-78-7

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Adenylosuccinic acid Related Antibodies

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Description

Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD)[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Adenylosuccinic acid (oral administration; 3-3000 µg/mL; 6 weeks) significantly improves the features of murine DMD, it decreases the number of centronucleated fibres, lipid accumulation, connective tissue infiltration and Ca2+ content of mdx tibialis anterior[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57Bl/10ScSn (normal wild-type strain; Con) and C57Bl/10mdx (mdx) mice[1]
Dosage: 3 µg/mL, 30 µg/mL, 300 µg/mL, 3000 µg/mL
Administration: 3 µg/mL for 3 days and 30 µg/mL for the next 4 days, and 300 µg/mL for one week, and then 3000 µg/mL for 6 weeks
Result: Ameliorated the symptoms of murine duchenne muscular dystrophy.
Molecular Weight

463.29

Formula

C14H18N5O11P
CAS No.
SMILES

O=C(C[C@H](NC1=C2N=CN(C2=NC=N1)[C@H]3[C@H](O)[C@H](O)[C@H](O3)COP(O)(O)=O)C(O)=O)O
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Adenylosuccinic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adenylosuccinic acid19046-78-7Adenylosuccinate Aspartyl adenylateEndogenous MetaboliteDuchennemusculardystrophyDMD metabolite nucleotidecycleInhibitorinhibitorinhibit

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