2. Anti-infection
  3. Bacterial Fungal Antibiotic
  4. Aerothionin

Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs).

For research use only. We do not sell to patients.

Aerothionin Chemical Structure

Aerothionin Chemical Structure

CAS No. : 28714-26-3

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Aerothionin Related Antibodies

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Description

Aerothionin is an antibiotic with potent antimicrobial efficacy against bacteria and fungi. Aerothionin exhibits antitumor efficacy against adrenal pheochromocytomas and extra-adrenal paragangliomas (PPGLs)[1][2].

In Vitro

Aerothionin (0-100 μM, 24h) inhibits prolifeartions of pheochromocytoma cells MPC and MTT, inhibits the MTT spheroid growth (10 μM, single dose)[1].
Aerothionin (0-100 μM, 24h) exhibits toxicity in normal endothelial cells HUVECs, stimulates slightly the viability of normal fibroblasts 3T3[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Aerothionin Related Antibodies

Cell Viability Assay[1]

Cell Line: MPC, MTT, HUVECs, 3T3
Concentration: 0-100 μM
Incubation Time: 24 h
Result: Inhibited proliferations of MPC, MTT and HUVECs, stimulated proliferation of 32T3.
Molecular Weight

818.10

Formula

C24H26Br4N4O8
CAS No.
SMILES

O[C@@H]1[C@@]2(C=C(C(OC)=C1Br)Br)CC(C(NCCCCNC(C3=NO[C@@]4([C@H](C(Br)=C(C(Br)=C4)OC)O)C3)=O)=O)=NO2
Structure Classification
Initial Source

Aplysina fistularis
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aerothionin Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aerothionin28714-26-3BacterialFungalAntibioticHUVECs3T3MPCMTTextra-adrenal paragangliomasPPGLInhibitorinhibitorinhibit

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