PRDX3 Antibody (YA909)

PRDX3 Antibody (YA909) is an unconjugated, approximately 28 kDa, human-derived, anti-PRDX3 (YA909) monoclonal antibody. PRDX3 Antibody (YA909) can be used for: WB, IF-Cell, IHC-P, FC, IP expriments in human background without labeling.

Thioredoxin-dependent peroxide reductase, mitochondrial is an enzyme that in humans is encoded by the PRDX3 gene. It is a member of the peroxiredoxin family of antioxidant enzymes. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.

10935

Predicted band size: 28 kDa

Affinity Purified

Mitochondrion

Non-conjugated

Neuroscience

Primary Antibody; Recombinant Rabbit Monoclonal Antibody

Human

Human

P30048

WB: 1:500-1:2,000；IF-Cell: 1:50-1:200；IHC-P: 1:50-1:200；FC: 1:50-1:100；IP: Use at an assay dependent concentration.

WB, IF-Cell, IHC-P, FC, IP

Liquid

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Synthetic peptide within Human Peroxiredoxin 3 aa 207-256 / 256.