60S ribosomal protein L7

Definition:

Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.

References:

[1]. Andreas M Anger, et al. Structures of the human and Drosophila 80S ribosome. Nature. 2013 May 2;497(7447):80-5. [Content Brief]

[2]. Xiaomeng Liang, et al. Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun. 2020 Jul 15;11(1):3542. [Content Brief]

[3]. Tatyana I Odintsova, et al. Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. J Protein Chem. 2003 Apr;22(3):249-58. [Content Brief]

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