Endonuclease domain-containing 1 protein

Definition:

May act as a DNase and a RNase. Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26.

References:

[1]. Emma J Fenech, et al. Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling. Elife. 2020 Jul 2;9:e57306. [Content Brief]

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