Pancreatic triacylglycerol lipase

Definition:

Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.

References:

[1]. A M van Bennekum, et al. Hydrolysis of retinyl esters by pancreatic triglyceride lipase. Biochemistry. 2000 Apr 25;39(16):4900-6. [Content Brief]

[2]. Cécilia Eydoux, et al. Further biochemical characterization of human pancreatic lipase-related protein 2 expressed in yeast cells. J Lipid Res. 2007 Jul;48(7):1539-49. [Content Brief]

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