Peptidyl-prolyl cis-trans isomerase FKBP14

Definition:

PPIase which accelerates the folding of proteins during protein synthesis. Has a preference for substrates containing 4-hydroxylproline modifications, including type III collagen. May also target type VI and type X collagens.

References:

[1]. Yoshihiro Ishikawa, et al. A substrate preference for the rough endoplasmic reticulum resident protein FKBP22 during collagen biosynthesis. J Biol Chem. 2014 Jun 27;289(26):18189-201. [Content Brief]

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