Peroxisomal membrane protein 11B

Definition:

Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface.

References:

[1]. M Schrader, et al. Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli. J Biol Chem. 1998 Nov 6;273(45):29607-14. [Content Brief]

[2]. Johannes Koch, et al. PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance. J Cell Sci. 2010 Oct 1;123(Pt 19):3389-400. [Content Brief]

[3]. Xiaoling Li, et al. The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11. J Biol Chem. 2003 May 9;278(19):17012-20. [Content Brief]

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