Polycystic kidney disease protein 1-like 3

Definition:

Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.

References:

[1]. Yong Yu, et al. Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nat Commun. 2012;3:1252. [Content Brief]

[2]. Airong Li, et al. Identification of two novel polycystic kidney disease-1-like genes in human and mouse genomes. Genomics. 2003 Jun;81(6):596-608. [Content Brief]

[3]. Taufiqul Huque, et al. Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue. PLoS One. 2009 Oct 8;4(10):e7347. [Content Brief]

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