Popeye domain-containing protein 3

Definition:

May play a role in the maintenance of heart function mediated, at least in part, through cAMP-binding. May play a role in the regulation of KCNK2/TREK-1-mediated current amplitude.

References:

[1]. John Vissing, et al. POPDC3 Gene Variants Associate with a New Form of Limb Girdle Muscular Dystrophy. Ann Neurol. 2019 Dec;86(6):832-843. [Content Brief]

[2]. B Andrée, et al. Isolation and characterization of the novel popeye gene family expressed in skeletal muscle and heart. Dev Biol. 2000 Jul 15;223(2):371-82. [Content Brief]

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