POU domain class 2-associating factor 2

Definition:

Transcriptional coactivator that specifically associates with POU2F3. This complex drives the development of tuft cells, a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues.

References:

[1]. Xiaoli S Wu, et al. OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. 2022 Jul;607(7917):169-175. [Content Brief]

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