Protein phosphatase 1 regulatory subunit 14D

Definition:

Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

References:

[1]. Qing-Rong Liu, et al. GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA. Biochem J. 2004 Jan 1;377(Pt 1):171-81. [Content Brief]

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