Protein phosphatase 1 regulatory subunit 21

Definition:

Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway.

References:

[1]. Annick Hendrickx, et al. Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem Biol. 2009 Apr 24;16(4):365-71. [Content Brief]

[2]. Atteeq U Rehman, et al. Biallelic loss of function variants in PPP1R21 cause a neurodevelopmental syndrome with impaired endocytic function. Hum Mutat. 2019 Mar;40(3):267-280. [Content Brief]

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