Protein POF1B

Definition:

Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development.

References:

[1]. Valeria Padovano, et al. The POF1B candidate gene for premature ovarian failure regulates epithelial polarity. J Cell Sci. 2011 Oct 1;124(Pt 19):3356-68. [Content Brief]

[2]. Arnaud Lacombe, et al. Disruption of POF1B binding to nonmuscle actin filaments is associated with premature ovarian failure. Am J Hum Genet. 2006 Jul;79(1):113-9. [Content Brief]

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