Citrulline-specific probe-rhodamine hydrate

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Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis.

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Citrulline-specific probe-rhodamine hydrate Chemical Structure

CAS No. : 2309313-01-5

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Description	Citrulline-specific probe-rhodamine hydrate is a specific probe for citrulline (Citrulline) combined with a rhodamine fluorescent group. Citrulline is the hydrolysis product of arginine catalyzed by protein arginine deiminase (PAD). PAD is abnormally activated in many diseases, leading to increased citrulline levels. Citrulline-specific probe-rhodamine hydrate is a biological probe that can identify diseases showing abnormal increases in PAD activity and may be effectively used in animal models of ulcerative colitis^[1].
Molecular Weight	731.75
Formula	C₃₉H₃₇N₇O₈
CAS No.	2309313-01-5
SMILES	O=CC(C1=CC(NC(C(C)N2N=NC(CNC(C3=CC=C4C(C(OC45C6=CC=C(N(C)C)C=C6OC7=CC(N(C)C)=CC=C75)=O)=C3)=O)=C2)=O)=CC=C1)=O.O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Bicker K L, Subramanian V, Chumanevich A A, et al. Seeing citrulline: development of a phenylglyoxal-based probe to visualize protein citrullination[J]. Journal of the American Chemical Society, 2012, 134(41): 17015-17018.