1. Immunology/Inflammation Metabolic Enzyme/Protease NF-κB
  2. COX Lipoxygenase NF-κB
  3. COX-2/15-LOX-IN-5

COX-2/15-LOX-IN-5 (Compound 4f) is a dual inhibitor of COX-2/15-LOX. COX-2/15-LOX-IN-5 attenuates increased NF-κB activation in RAW 264.7 macrophages mediated by lipopolysaccharide (HY-D1056). COX-2/15-LOX-IN-5 has anti-inflammatory and antioxidant activities.

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COX-2/15-LOX-IN-5 Chemical Structure

COX-2/15-LOX-IN-5 Chemical Structure

CAS No. : 443790-30-5

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Description

COX-2/15-LOX-IN-5 (Compound 4f) is a dual inhibitor of COX-2/15-LOX. COX-2/15-LOX-IN-5 attenuates increased NF-κB activation in RAW 264.7 macrophages mediated by lipopolysaccharide (HY-D1056). COX-2/15-LOX-IN-5 has anti-inflammatory and antioxidant activities[1].

Molecular Weight

443.52

Formula

C25H21N3O3S

CAS No.
SMILES

COC1=CC=C(C=C1)NC(CSC2=N/C(C(N2C3=CC=CC=C3)=O)=C\C4=CC=CC=C4)=O

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Product Name:
COX-2/15-LOX-IN-5
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HY-163355
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