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  4. Disuccinimidyl sebacate

Disuccinimidyl sebacate  (Synonyms: DSSeb; Sebacic acid bis N-succinimidyl ester)

Cat. No.: HY-119523 Purity: ≥97.0%
COA Handling Instructions

Molarity Calculator

Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides.

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Disuccinimidyl sebacate Chemical Structure

Disuccinimidyl sebacate Chemical Structure

CAS No. : 23024-29-5

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Based on 1 publication(s) in Google Scholar

Disuccinimidyl sebacate Related Antibodies

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Description

Disuccinimidyl sebacate (DSSeb) is a cross-linker that can be used in the synthesis of the intermolecular cross-linked peptides[1].

Molecular Weight

396.39

Formula

C18H24N2O8
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCCCCCCCC(ON1C(CCC1=O)=O)=O)ON2C(CCC2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (126.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5228 mL 12.6138 mL 25.2277 mL
5 mM 0.5046 mL 2.5228 mL 5.0455 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

COA (245 KB) HNMR (133 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5228 mL 12.6138 mL 25.2277 mL 63.0692 mL
5 mM 0.5046 mL 2.5228 mL 5.0455 mL 12.6138 mL
10 mM 0.2523 mL 1.2614 mL 2.5228 mL 6.3069 mL
15 mM 0.1682 mL 0.8409 mL 1.6818 mL 4.2046 mL
20 mM 0.1261 mL 0.6307 mL 1.2614 mL 3.1535 mL
25 mM 0.1009 mL 0.5046 mL 1.0091 mL 2.5228 mL
30 mM 0.0841 mL 0.4205 mL 0.8409 mL 2.1023 mL
40 mM 0.0631 mL 0.3153 mL 0.6307 mL 1.5767 mL
50 mM 0.0505 mL 0.2523 mL 0.5046 mL 1.2614 mL
60 mM 0.0420 mL 0.2102 mL 0.4205 mL 1.0512 mL
80 mM 0.0315 mL 0.1577 mL 0.3153 mL 0.7884 mL
100 mM 0.0252 mL 0.1261 mL 0.2523 mL 0.6307 mL
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Disuccinimidyl sebacate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Disuccinimidyl sebacate23024-29-5DSSeb Sebacic acid bis N-succinimidyl esterBiochemical Assay ReagentsInhibitorinhibitorinhibit

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