1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. FL118-14-Propanol

FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice.

For research use only. We do not sell to patients.

FL118-14-Propanol Chemical Structure

FL118-14-Propanol Chemical Structure

CAS No. : 2821768-98-1

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5 mg USD 405 In-stock
10 mg USD 650 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice[1].

Molecular Weight

450.44

Formula

C24H22N2O7

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OCCCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (222.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2201 mL 11.1003 mL 22.2005 mL
5 mM 0.4440 mL 2.2201 mL 4.4401 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.69%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2201 mL 11.1003 mL 22.2005 mL 55.5013 mL
5 mM 0.4440 mL 2.2201 mL 4.4401 mL 11.1003 mL
10 mM 0.2220 mL 1.1100 mL 2.2201 mL 5.5501 mL
15 mM 0.1480 mL 0.7400 mL 1.4800 mL 3.7001 mL
20 mM 0.1110 mL 0.5550 mL 1.1100 mL 2.7751 mL
25 mM 0.0888 mL 0.4440 mL 0.8880 mL 2.2201 mL
30 mM 0.0740 mL 0.3700 mL 0.7400 mL 1.8500 mL
40 mM 0.0555 mL 0.2775 mL 0.5550 mL 1.3875 mL
50 mM 0.0444 mL 0.2220 mL 0.4440 mL 1.1100 mL
60 mM 0.0370 mL 0.1850 mL 0.3700 mL 0.9250 mL
80 mM 0.0278 mL 0.1388 mL 0.2775 mL 0.6938 mL
100 mM 0.0222 mL 0.1110 mL 0.2220 mL 0.5550 mL
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FL118-14-Propanol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
FL118-14-Propanol
Cat. No.:
HY-156856
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