ARFRP1 - ADP ribosylation factor related protein 1 Gene

Homo sapiens

Also known as ARP; Arp1; ARL18

Gene ID: 10139 | Gene type: protein coding

About ARFRP1

Cytogenetic location: 20q13.33 Genomic coordinates (GRCh38): 20:63,698,647-63,707,976 (from NCBI)

Ubiquitous expression in spleen (RPKM 7.0), fat (RPKM 5.7) and 25 other tissues.

Summary

The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]

ARFRP1 Products(8)

mRNA	Protein	Name
NM_001134758.4	NP_001128230.1	ADP-ribosylation factor-related protein 1 isoform b
NM_001267544.3	NP_001254473.1	ADP-ribosylation factor-related protein 1 isoform c
NM_001267545.3	NP_001254474.1	ADP-ribosylation factor-related protein 1 isoform d
NM_001267546.3	NP_001254475.1	ADP-ribosylation factor-related protein 1 isoform e
NM_001267547.3	NP_001254476.1	ADP-ribosylation factor-related protein 1 isoform a
NM_001267548.3	NP_001254477.1	ADP-ribosylation factor-related protein 1 isoform a
NM_001267549.3	NP_001254478.1	ADP-ribosylation factor-related protein 1 isoform b
NM_003224.6	NP_003215.1	ADP-ribosylation factor-related protein 1 isoform a

ARFRP1 Protein Structure

Arf

0
100
201 a.a.

Protein Preferred Names

Protein Names

ADP-ribosylation factor-related protein 1

ARF-related protein 1

Related Diseases

Diseases

Alias

Wiskott-Aldrich Syndrome

WAS	Eczema-Thrombocytopenia-Immunodeficiency Syndrome
Immunodeficiency 2	Aldrich Syndrome
Imd2	Wiskott-Aldrich Syndrome 1
Was1	Wiskott Syndrome
Wiskott Aldrich Syndrome	Eczema Thrombocytopenia Immunodeficiency Syndrome
Imd 2

Hematocele Of Tunica Vaginalis Testis

Hematocele

Male Hematocele

Mental Retardation, Enteropathy, Deafness, Peripheral Neuropathy, Ichthyosis, And Keratoderma

Mednik Syndrome	Erythrokeratodermia Variabilis 3
MEDNIK	Ekv3
Erythrokeratodermia Variabilis, Kamouraska Type	Mental Retardation, Enteropathy, Deafness, Neuropathy, Ichthyosis, Keratodermia
Intellectual Disability-Enteropathy-Deafness-Peripheral Neuropathy-Ichthyosis-Keratodermia Syndrome	Intellectual Disability-Enteropathy-Hearing Loss-Peripheral Neuropathy-Ichthyosis-Keratodermia Syndrome
Intellectual Disability, Enteropathy, Deafness, Peripheral Neuropathy, Ichthyosis, And Keratoderma	Erythrokeratodermia Variabilis Kamouraska Type
Mental Retardation, Enteropathy, Deafness, Peripheral Neuropathy, Ichthyosis, Keratoderma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00906	ARFRP1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ARFRP1	VGNC	VGNC:98510
Rattus norvegicus	ARFRP1	RGD	RGD:621683
Bos taurus	ARFRP1	VGNC	VGNC:26069
Macaca mulatta	ARFRP1	VGNC	VGNC:70003
Mus musculus	ARFRP1	MGD	MGI:1923938
Canis familiaris	ARFRP1	VGNC	VGNC:38040

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