2. Gene
  3. LMAN2 - lectin, mannose binding 2 Gene

LMAN2 - lectin, mannose binding 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GP36B; VIP36; C5orf8

Gene ID: 10960 | Gene type: protein coding

About LMAN2

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:177,331,567-177,351,668 (from NCBI)

This gene has 11 transcripts (splice variants), 208 orthologues and 3 paralogues. Ubiquitous expression in thyroid (RPKM 56.0), testis (RPKM 45.6) and 25 other tissues.

Summary

This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq, Oct 2008]

LMAN2 Products(1)

mRNA Protein Name
NM_006816.3 NP_006807.1 vesicular integral-membrane protein VIP36 precursor

LMAN2 Protein Structure

Lectin_leg-like

Lectin_leg-like: Legume-like lectin family (53 - 277)

  • 0
  • 100
  • 200
  • 300
  • 356 a.a.
Protein Preferred Names Protein Names

vesicular integral-membrane protein VIP36

epididymis secretory sperm binding protein

Recombinant LMAN2 Proteins

Cat. No. Product Name Accession Purity
HY-P71151 LMAN2 Protein, Human (HEK293, His) Q12907 (D45-R322) ≥95%

Related Diseases

Diseases Alias
Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07704 LMAN2 Human Pre-designed siRNA Set A / Unkown
HY-RS07705 LMAN2L Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus LMAN2 VGNC VGNC:63246
Canis familiaris LMAN2 VGNC VGNC:42708
Mus musculus LMAN2 MGD MGI:1914140
Rattus norvegicus LMAN2 RGD RGD:1308965
Macaca mulatta LMAN2 VGNC VGNC:74302
Bos taurus LMAN2 VGNC VGNC:30920
Others LMAN2 NCBI