KCTD12 - potassium channel tetramerization domain containing 12 Gene

Homo sapiens

Also known as PFET1; PFETIN; C13orf2

Gene ID: 115207 | Gene type: protein coding

About KCTD12

Cytogenetic location: 13q22.3 Genomic coordinates (GRCh38): 13:76,880,175-76,886,405 (from NCBI)

This gene has 1 transcript (splice variant), 257 orthologues and 13 paralogues.

Summary

Enables identical protein binding activity. Predicted to be involved in protein homooligomerization. Predicted to act upstream of or within regulation of G protein-coupled receptor signaling pathway. Predicted to be located in cell projection. Predicted to be part of receptor complex. Predicted to be active in postsynaptic membrane and presynaptic membrane. [provided by Alliance of Genome Resources, Apr 2022]

KCTD12 Products(1)

mRNA	Protein	Name
NM_138444.4	NP_612453.1	BTB/POZ domain-containing protein KCTD12

KCTD12 Protein Structure

BTB_2

0
100
200
300
325 a.a.

Protein Preferred Names

Protein Names

BTB/POZ domain-containing protein KCTD12

potassium channel tetramerisation domain containing 12

Related Diseases

Diseases

Alias

Scalp-Ear-Nipple Syndrome

Finlay-Marks Syndrome	Sen Syndrome
SENS	Scalp Ear Nipple Syndrome
Hereditary Syndrome Of Lumpy Scalp, Odd Ears And Rudimentary Nipples	Hereditary Syndrome Of Lumpy Scalp, Odd Ears, And Rudimentary Nipples
Indian Childhood Cirrhosis

Bipolar I Disorder

Manic Depression Nos	Manic-Depressive Illness
Bipolar Disorder Nos

Gastrointestinal Stromal Tumor

GIST	Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Sarcoma	Gastrointestinal Stromal Tumor, Familial
Gant	Gastrointestinal Stromal Tumour
Stromal Tumor Of Gastrointestinal Tract	Stromal Tumour Of Gastrointestinal Tract
Gastrointestinal Stromal Neoplasm	Paraganglioma And Gastric Stromal Sarcoma
Plexosarcoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07189	KCTD12 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	KCTD12	RGD	RGD:1309421
Felis catus	KCTD12	VGNC	VGNC:97471
Bos taurus	KCTD12	VGNC	VGNC:30502
Macaca mulatta	KCTD12	VGNC	VGNC:106266
Mus musculus	KCTD12	MGD	MGI:2145823
Canis familiaris	KCTD12	VGNC	VGNC:42301

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