BATF2 - basic leucine zipper ATF-like transcription factor 2 Gene

Homo sapiens

Also known as SARI

Gene ID: 116071 | Gene type: protein coding

About BATF2

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:64,987,945-64,996,971 (from NCBI)

This gene has 5 transcripts (splice variants), 238 orthologues and 8 paralogues. Broad expression in spleen (RPKM 7.0), appendix (RPKM 4.9) and 23 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in defense response to protozoan; myeloid dendritic cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

BATF2 Products(3)

mRNA	Protein	Name
NM_001300807.2	NP_001287736.1	basic leucine zipper transcriptional factor ATF-like 2 isoform 2
NM_001300808.2	NP_001287737.1	basic leucine zipper transcriptional factor ATF-like 2 isoform 3
NM_138456.4	NP_612465.3	basic leucine zipper transcriptional factor ATF-like 2 isoform 1

BATF2 Protein Structure

bZIP_1

0
100
200
274 a.a.

Protein Preferred Names

Protein Names

basic leucine zipper transcriptional factor ATF-like 2

B-ATF-2

Related Diseases

Diseases

Alias

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01372	BATF2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	BATF2	VGNC	VGNC:38386
Felis catus	BATF2	VGNC	VGNC:60074
Macaca mulatta	BATF2	VGNC	VGNC:70127
Bos taurus	BATF2	VGNC	VGNC:26426
Rattus norvegicus	BATF2	RGD	RGD:1311481
Mus musculus	BATF2	MGD	MGI:1921731

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