LYPLAL1 - lysophospholipase like 1 Gene

Homo sapiens

Also known as Q96AV0

Gene ID: 127018 | Gene type: protein coding

About LYPLAL1

Cytogenetic location: 1q41 Genomic coordinates (GRCh38): 1:219,173,878-219,445,496 (from NCBI)

This gene has 12 transcripts (splice variants), 173 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 3.2), heart (RPKM 2.4) and 25 other tissues.

Summary

Predicted to enable carboxylic ester hydrolase activity and palmitoyl-(protein) hydrolase activity. Predicted to be involved in protein depalmitoylation. Predicted to act upstream of or within negative regulation of Golgi to plasma membrane protein transport. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

LYPLAL1 Products(7)

mRNA	Protein	Name
NM_001300769.2	NP_001287698.1	lysophospholipase-like protein 1 isoform b
NM_001300770.2	NP_001287699.1	lysophospholipase-like protein 1 isoform c
NM_001300771.2	NP_001287700.1	lysophospholipase-like protein 1 isoform d
NM_001300772.2	NP_001287701.1	lysophospholipase-like protein 1 isoform d
NM_001350628.2	NP_001337557.1	lysophospholipase-like protein 1 isoform e
NM_001350629.2	NP_001337558.1	lysophospholipase-like protein 1 isoform f
NM_138794.5	NP_620149.2	lysophospholipase-like protein 1 isoform a

LYPLAL1 Protein Structure

Abhydrolase_2

0
100
200
237 a.a.

Protein Preferred Names

Protein Names

lysophospholipase-like protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-124700	LYPLAL1-IN-1	Inhibitor	≥99.0%	Unkown
HY-147049	PAL-4	Activator	/	Unkown
HY-RS07923	LYPLAL1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	LYPLAL1	MGD	MGI:2385115
Macaca mulatta	LYPLAL1	VGNC	VGNC:74319
Felis catus	LYPLAL1	VGNC	VGNC:63344
Bos taurus	LYPLAL1	VGNC	VGNC:31107
Rattus norvegicus	LYPLAL1	RGD	RGD:1311195
Canis familiaris	LYPLAL1	VGNC	VGNC:42892

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