Cnr2 - cannabinoid receptor 2 (macrophage) Gene

Mus musculus

Also known as CB2; CB-2; CB2-R

Gene ID: 12802 | Gene type: protein coding

About Cnr2

Chromosome 4: 135,622,705-135,647,518 forward strand.GRCm39:CM000997.3

This gene has 2 transcripts (splice variants), 196 orthologues, 18 paralogues and is associated with 18 phenotypes. Biased expression in spleen adult (RPKM 19.7), mammary gland adult (RPKM 6.) and 6 other tissues.

Summary

Predicted to enable Cannabinoid Receptor activity. Acts upstream of or within leukocyte chemotaxis. Predicted to be located in dendrite; endoplasmic reticulum; and neuronal cell body. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Orthologous to human CNR2 (Cannabinoid Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnr2 Products(2)

mRNA	Protein	Name
NM_009924.4	NP_034054.3	cannabinoid receptor 2
NM_001305278.1	NP_001292207.1	cannabinoid receptor 2

Cnr2 Protein Structure

7tmA_CB2

0
100
200
300
347 a.a.

Protein Preferred Names

Protein Names

cannabinoid receptor 2

cannabinoid receptor 2 (spleen)

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15703	QNZ46	Antagonist	98.80%	Unkown
HY-107713	PPDA	Antagonist	/	Unkown
HY-RS02917	CNR2 Human Pre-designed siRNA Set A		/	Unkown
HY-RS02918	Cnr2 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS02919	Cnr2 Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cnr2	NCBI	NCBI:1269

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