2. Gene
  3. Egfr - epidermal growth factor receptor Gene

Egfr - epidermal growth factor receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Wa5; wa2; Erbb; Errp; wa-2; Errb1; 9030024J15Rik

Gene ID: 13649 | Gene type: protein coding

About Egfr

Chromosome 11: 16,702,203-16,868,158 forward strand.GRCm39:CM001004.3

This gene has 5 transcripts (splice variants), 283 orthologues, 53 paralogues and is associated with 180 phenotypes. Broad expression in liver adult (RPKM 26.7), liver E18 (RPKM 8.7) and 15 other tissues.

Summary

Enables epidermal growth factor binding activity and epidermal growth factor-activated receptor activity. Involved in cellular response to amino acid stimulus and positive regulation of fibroblast proliferation. Acts upstream of or within several processes, including animal organ development; epidermal growth factor receptor signaling pathway; and protein autophosphorylation. Located in several cellular components, including basolateral plasma membrane; endocytic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; brain; integumental system; limb; and respiratory system. Used to study Coronavirus infectious disease and aortic valve disease. Human ortholog(s) of this gene implicated in several diseases, including colorectal cancer; lung non-small cell carcinoma (multiple); pancreatic cancer; prostate cancer; and pulmonary tuberculosis. Orthologous to human EGFR (epidermal growth factor receptor). [provided by Alliance of Genome Resources, Apr 2022]

Egfr Products(2)

mRNA Protein Name
NM_207655.2 NP_997538.1 epidermal growth factor receptor isoform 1 precursor
NM_007912.4 NP_031938.1 epidermal growth factor receptor isoform 2 precursor

Egfr Protein Structure

Recep_L_domain

Recep_L_domain: pfam01030 (56 - 167)

Furin-like

Furin-like: pfam00757 (183 - 334)

Recep_L_domain

Recep_L_domain: pfam01030 (361 - 480)

GF_recep_IV

GF_recep_IV: pfam14843 (504 - 635)

TM_ErbB1

TM_ErbB1: cd12093 (633 - 678)

PTKc_EGFR

PTKc_EGFR: cd05108 (705 - 1017)

  • 0
  • 200
  • 400
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  • 800
  • 1000
  • 1210 a.a.
Protein Preferred Names Protein Names

epidermal growth factor receptor

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

waved 2

Recombinant Egfr Proteins

Cat. No. Product Name Accession Purity
HY-P72988 EGFR Protein, Mouse (HEK293, Fc) Q01279 (L25-S647) ≥95%
HY-P72989 EGFR Protein, Mouse (HEK293, His) Q01279 (M1-S647) ≥95%

Related Agents

Approval
Bioactive Molecules (41)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15772 Osimertinib Inhibitor 99.96% Yes
HY-50895 Gefitinib Inhibitor 99.94% Yes
HY-50896 Erlotinib Inhibitor 99.99% Yes
HY-10261 Afatinib Inhibitor 99.93% Yes
HY-138298A Trastuzumab deruxtecan Inhibitor 99.90% Unkown
HY-50898 Lapatinib Inhibitor 99.83% Yes
HY-P9921 Trastuzumab emtansine Inhibitor 99.74% Unkown
HY-32721 Neratinib Inhibitor 99.59% Yes
HY-16069 Tucatinib Inhibitor 99.82% Yes
HY-138298 Trastuzumab deruxtecan (solution) Inhibitor 99.64% Unkown
HY-13272 Dacomitinib Inhibitor 99.74% Yes
HY-P9985 Disitamab vedotin Inhibitor ≥99.0% Unkown
HY-15772A Osimertinib mesylate Inhibitor 99.95% Yes
HY-135815 Mobocertinib Inhibitor 99.60% Yes
HY-12008 Erlotinib Hydrochloride Inhibitor 99.93% Yes
HY-104065 Pyrotinib Inhibitor 99.80% Unkown
HY-112870A Firmonertinib mesylate Inhibitor 99.97% Unkown
HY-109061 Lazertinib Inhibitor 99.07% Unkown
HY-112823 Almonertinib Inhibitor 99.98% Unkown
HY-50895A Gefitinib hydrochloride Inhibitor 99.85% Yes
HY-15164A Icotinib Inhibitor 99.99% Yes
HY-19730 Olmutinib Inhibitor 99.88% Unkown
HY-10261A Afatinib dimaleate Inhibitor 99.88% Yes
HY-N0281 Daphnetin Inhibitor 99.86% Unkown
HY-79077 Osimertinib dimesylate Inhibitor 99.96% Yes
HY-50898A Lapatinib ditosylate Inhibitor 99.95% Yes
HY-15164 Icotinib Hydrochloride Inhibitor 99.81% Yes
HY-104065B Pyrotinib dimaleate Inhibitor 98.56% Unkown
HY-50898B Lapatinib ditosylate monohydrate Inhibitor 99.78% Yes
HY-135815A Mobocertinib succinate Inhibitor 99.61% Yes
HY-112823A Almonertinib mesylate Inhibitor 99.85% Unkown
HY-112823B Almonertinib hydrochloride Inhibitor 99.77% Unkown
HY-118263 Dacomitinib hydrate Inhibitor 99.03% Unkown
HY-32721B Neratinib maleate Inhibitor 99.83% Yes
HY-P9921A Trastuzumab emtansine (solution) 99.01% Unkown
HY-112870 Firmonertinib Inhibitor / Unkown
HY-10261D Afatinib oxalate Inhibitor / Unkown
HY-135815B Mobocertinib mesylate Inhibitor / Unkown
HY-50898C Lapatinib tosylate Inhibitor / Unkown
HY-50895R Gefitinib (Standard) Inhibitor / Unkown
HY-12008A Erlotinib mesylate Inhibitor / Unkown
Inhibitory Antibodies (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9907 Trastuzumab Inhibitor 99.80% Unkown
HY-P9905 Cetuximab Inhibitor 99.70% Unkown
HY-P9912 Pertuzumab Inhibitor 99.80% Unkown
HY-P9977 Amivantamab Inhibitor 99.90% Unkown
HY-P99041 Panitumumab Inhibitor 98.80% Unkown
HY-P9968 Nimotuzumab Inhibitor 96.70% Unkown
HY-P99030 Margetuximab Inhibitor 98.90% Unkown
HY-P9964 Necitumumab Inhibitor 95.00% Unkown
Clinical Phase
Bioactive Molecules (52)
Cat. No. Product Name Effect
Purity Phase
HY-14596 Genistein Inhibitor 99.86% Phase 4
HY-50895G Gefitinib (GMP) Inhibitor / Phase 4
HY-132842 Sunvozertinib Inhibitor 99.92% Phase 3
HY-15729 Rociletinib Inhibitor 99.79% Phase 3
HY-18750 Zorifertinib Inhibitor 99.76% Phase 3
HY-13314 Tesevatinib Inhibitor 99.21% Phase 3
HY-10530 Varlitinib Inhibitor 98.03% Phase 3
HY-19816A Avitinib maleate Inhibitor ≥98.0% Phase 3
HY-19816 Avitinib Inhibitor 99.90% Phase 3
HY-16069A Tucatinib hemiethanolate Inhibitor 99.97% Phase 3
HY-19803 Naquotinib mesylate Inhibitor 98.02% Phase 3
HY-138751 limertinib Inhibitor 98.01% Phase 3
HY-15729A Rociletinib hydrobromide Inhibitor 98.04% Phase 3
HY-19729 Naquotinib Inhibitor 98.71% Phase 3
HY-144680 BLU-945 Inhibitor 99.90% Phase 2
HY-32718 Pelitinib Inhibitor 98.80% Phase 2
HY-10367 Canertinib Inhibitor 99.95% Phase 2
HY-112299 Zipalertinib Inhibitor 99.81% Phase 2
HY-10333 BMS-690514 Inhibitor 99.07% Phase 2
HY-136789 Tuxobertinib Inhibitor 99.94% Phase 2
HY-10045 AEE788 Inhibitor 99.13% Phase 2
HY-12872 Nazartinib Inhibitor 99.48% Phase 2
HY-12972 Mavelertinib Inhibitor 99.21% Phase 2
HY-19985 PF-06459988 Inhibitor 98.87% Phase 2
HY-10367A Canertinib dihydrochloride Inhibitor 99.12% Phase 2
HY-107367A Epertinib hydrochloride Inhibitor 98.25% Phase 2
HY-17632 Tarloxotinib bromide Inhibitor 99.26% Phase 2
HY-19909 NRC-2694 Antagonist 99.45% Phase 2
HY-107367 Epertinib Inhibitor ≥98.0% Phase 2
HY-12872A Nazartinib mesylate Inhibitor / Phase 2
HY-106204 Nelipepimut-S / Phase 2
HY-10223 CUDC-101 Inhibitor 99.19% Phase 1
HY-13501 Mubritinib Inhibitor 99.91% Phase 1
HY-18957 Lifirafenib Inhibitor 98.73% Phase 1
HY-15196 TAK-285 Inhibitor 99.70% Phase 1
HY-10322 Falnidamol Inhibitor 99.05% Phase 1
HY-B0794B AZ7550 Mesylate Inhibitor 99.24% Phase 1
HY-101820 Simotinib Inhibitor 99.70% Phase 1
HY-12010 BMS-599626 Hydrochloride Inhibitor 99.68% Phase 1
HY-10346A AV-412 free base Inhibitor 98.33% Phase 1
HY-111553 TAS0728 Inhibitor 99.15% Phase 1
HY-128778 DBPR112 Inhibitor 98.37% Phase 1
HY-103443 HKI-357 Inhibitor 99.65% Phase 1
HY-104066 Theliatinib Inhibitor 99.77% Phase 1
HY-139300A Epitinib succinate Inhibitor 99.01% Phase 1
HY-116437 Selatinib Inhibitor 99.83% Phase 1
HY-10346 AV-412 Inhibitor 99.17% Phase 1
HY-B0794A AZ7550 hydrochloride Inhibitor 98.66% Phase 1
HY-15732 BGB-102 Inhibitor 97.10% Phase 1
HY-104066A Theliatinib tartrate / Phase 1
HY-139300 Epitinib Inhibitor / Phase 1
HY-10251 BMS-599626 Inhibitor / Phase 1
Inhibitory Antibodies (30)
Cat. No. Product Name Effect
Purity Phase
HY-P9907A Trastuzumab (anti-HER2) Inhibitor 99.62% Phase 4
HY-P99854 Disitamab Inhibitor ≥95.0% Phase 4
HY-P99041A Panitumumab (anti-EGFR) Inhibitor 98.00% Phase 4
HY-P99969 Inetetamab Inhibitor 96.54% Phase 4
HY-P99275 Patritumab Inhibitor 98.94% Phase 3
HY-P99380 Zanidatamab Inhibitor 95.06% Phase 3
HY-P99849 Depatuxizumab Inhibitor 99.58% Phase 3
HY-P99155 Zalutumumab 98.26% Phase 3
HY-P99676 Izalontamab Inhibitor 99.03% Phase 3
HY-P99455 Bafisontamab Inhibitor 96.00% Phase 3
HY-P99437 Anbenitamab Inhibitor 99.22% Phase 3
HY-P99831 Coprelotamab / Phase 3
HY-P99630 Gancotamab Inhibitor / Phase 3
HY-P99268 Seribantumab Inhibitor ≥95.0% Phase 2
HY-P99507 Zenocutuzumab Inhibitor 99.20% Phase 2
HY-P99406 Petosemtamab Degrader 95.00% Phase 2
HY-P9969 Matuzumab 98.12% Phase 2
HY-P99936 Elgemtumab Inhibitor 96.80% Phase 2
HY-P99618 Fidasimtamab Inhibitor 95.00% Phase 2
HY-P99216 Ponezumab Inhibitor 95.00% Phase 2
HY-P99715 Losatuxizumab Inhibitor 95.00% Phase 2
HY-P99866 Duligotuzumab 97.93% Phase 2
HY-P990049 Becotatug Inhibitor 98.44% Phase 2
HY-P99296 Intetumumab Inhibitor 99.24% Phase 2
HY-P99628 Futuximab Inhibitor / Phase 2
HY-P99295 Imgatuzumab Inhibitor / Phase 2
HY-P99605 Cinrebafusp alfa Inhibitor 98.53% Phase 2
HY-P99672 Istiratumab Inhibitor / Phase 2
HY-P99304 Lumretuzumab Inhibitor 95.00% Phase 1
HY-P99461 Barecetamab Inhibitor 97.96% Phase 1
Pre-clinical Phase
Bioactive Molecules (417)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12000 AG490 Inhibitor 99.97% Unkown
HY-13524 AG-1478 Inhibitor 99.22% Unkown
HY-101084 NSC 228155 Activator ≥98.0% Unkown
HY-13050 Sapitinib Inhibitor 99.93% Unkown
HY-13595 Chrysophanol Inhibitor 99.77% Unkown
HY-100848 TX1-85-1 Inhibitor 98.04% Unkown
HY-16558 Butein Inhibitor 99.95% Unkown
HY-14346 PD153035 Inhibitor 98.83% Unkown
HY-N2409 Delphinidin chloride Inhibitor ≥98.0% Unkown
HY-123921 Gefitinib-based PROTAC 3 Inhibitor 99.98% Unkown
HY-N0280 Corosolic acid 99.23% Unkown
HY-100213 EAI045 Inhibitor 99.08% Unkown
HY-15644 Tyrphostin 23 Inhibitor 99.43% Unkown
HY-129550 BI-4020 Inhibitor 99.28% Unkown
HY-12001 WZ-3146 Inhibitor 99.63% Unkown
HY-13896 PD168393 Inhibitor 98.60% Unkown
HY-B0793 AZ-5104 Inhibitor 99.70% Unkown
HY-18609 PD158780 Inhibitor 99.56% Unkown
HY-14674 CP-724714 Inhibitor 98.53% Unkown
HY-12026 WZ4002 Inhibitor 99.76% Unkown
HY-W016412 Coenzyme Q0 Inhibitor 99.88% Unkown
HY-111138 CZC-8004 Inhibitor 99.81% Unkown
HY-20878 Tyrphostin AG 879 Inhibitor 99.85% Unkown
HY-15844 AG-825 Inhibitor 98.02% Unkown
HY-13427 Allitinib tosylate Inhibitor 99.83% Unkown
HY-N2450 Sulforaphene Inhibitor 99.80% Unkown
HY-15730 Poziotinib Inhibitor 99.96% Unkown
HY-147183B JBJ-09-063 hydrochloride Inhibitor 99.37% Unkown
HY-13895 WHI-P154 Inhibitor 99.39% Unkown
HY-109189 Rezivertinib Inhibitor 99.43% Unkown
HY-135805A (Rac)-JBJ-04-125-02 Inhibitor ≥95.0% Unkown
HY-150024 BI-4142 Inhibitor 98.39% Unkown
HY-P1845A PACAP-38 (31-38), human, mouse, rat TFA Inducer 99.59% Unkown
HY-144880 SC209 Inhibitor 99.52% Unkown
HY-78869 Mutated EGFR-IN-1 Inhibitor 99.84% Unkown
HY-19815 Olafertinib Inhibitor 99.51% Unkown
HY-147183A JBJ-09-063 TFA Inhibitor 99.64% Unkown
HY-14596R Genistein (Standard) Inhibitor 99.31% Unkown
HY-P1845 PACAP-38 (31-38), human, mouse, rat Inducer 99.25% Unkown
HY-10531 ARRY-380 analog Inhibitor 99.19% Unkown
HY-108052 Delphinidin 3-glucoside chloride Inhibitor 99.83% Unkown
HY-14596S Genistein-d4 Inhibitor 98.81% Unkown
HY-10325 CL-387785 Inhibitor 98.05% Unkown
HY-15769 WHI-P180 Inhibitor 99.62% Unkown
HY-128862 EGFR-IN-7 Inhibitor 99.76% Unkown
HY-107364 MTX-211 Inhibitor ≥98.0% Unkown
HY-137191 CH7233163 Inhibitor 99.61% Unkown
HY-43533 Tarlox-TKI Inhibitor 97.03% Unkown
HY-123578 NSC689857 Inhibitor 99.65% Unkown
HY-134877 BAY 2476568 Inhibitor 98.05% Unkown
HY-12029 WZ8040 Inhibitor 99.22% Unkown
HY-150023 BI-1622 Inhibitor 98.97% Unkown
HY-137433 Befotertinib Inhibitor 99.96% Unkown
HY-142283AS Dosimertinib mesylate Inhibitor 99.44% Unkown
HY-136430 JCN037 Inhibitor 99.76% Unkown
HY-147941A MS9427 TFA Degrader 99.01% Unkown
HY-17499 EGFR-IN-12 Inhibitor 99.40% Unkown
HY-100499 Tyrphostin AG 528 Inhibitor ≥98.0% Unkown
HY-15801 HG-14-10-04 Inhibitor 99.09% Unkown
HY-107459 (E/Z)-AG490 Inhibitor 99.97% Unkown
HY-101042 AG-494 Inhibitor 99.31% Unkown
HY-101960A Tyrphostin A51 Inhibitor ≥99.0% Unkown
HY-153268 BDTX-1535 Inhibitor 99.03% Unkown
HY-112411 PD 174265 Inhibitor 98.72% Unkown
HY-139920 Oritinib Inhibitor 99.18% Unkown
HY-132842A (S)-Sunvozertinib Inhibitor 99.14% Unkown
HY-138627A AST5902 trimesylate Inhibitor 99.87% Unkown
HY-112420 EGFR/ErbB-2/ErbB-4 inhibitor-2 Inhibitor 99.69% Unkown
HY-117155 PKI-166 Inhibitor 99.58% Unkown
HY-103440 EGFR/ErbB-2/ErbB-4 inhibitor-3 Inhibitor 98.19% Unkown
HY-103566 LY456236 Inhibitor 99.81% Unkown
HY-124813 PDZ1i Inhibitor 99.29% Unkown
HY-155537 YK-029A Inhibitor 99.50% Unkown
HY-124674A CCT365623 hydrochloride Inhibitor 98.11% Unkown
HY-112293 GW2974 99.54% Unkown
HY-N0211 Cyasterone Inhibitor 99.58% Unkown
HY-12013 PD153035 Hydrochloride Inhibitor 98.78% Unkown
HY-119944 JND3229 Inhibitor 99.78% Unkown
HY-153110A Larotinib mesylate hydrate Inhibitor 98.66% Unkown
HY-141481 DP-C-4 Inhibitor 99.72% Unkown
HY-N6577 Astragaloside VI 99.95% Unkown
HY-120590 Ruserontinib Inhibitor 99.82% Unkown
HY-101429 RG13022 Inhibitor ≥95.0% Unkown
HY-112345 PD-089828 Inhibitor 98.07% Unkown
HY-123952 RTC-5 Inhibitor 99.89% Unkown
HY-N2510 Myristicin Inhibitor 99.89% Unkown
HY-150611 EGFR-IN-70 Inhibitor 99.16% Unkown
HY-101426 RG14620 Inhibitor 98.09% Unkown
HY-19617B EGFR-IN-1 TFA Inhibitor 99.38% Unkown
HY-N4201 β-Hydroxyisovalerylshikonin Inhibitor 99.83% Unkown
HY-15772S Osimertinib-d6 Inhibitor 99.97% Unkown
HY-18603 FIIN-3 Inhibitor 99.66% Unkown
HY-155079 DZD1516 98.31% Unkown
HY-157229 STX-721 Inhibitor / Unkown
HY-147219A SIAIS164018 hydrochloride Inhibitor 99.84% Unkown
HY-W013857 Lavendustin C Inhibitor 98.32% Unkown
HY-41404 Piperonylic acid 99.86% Unkown
HY-P1855 HER2/neu (654-662) GP2 98.04% Unkown
HY-144304 PROTAC EGFR degrader 2 Inhibitor 95.61% Unkown
HY-P5314 OK2 Inhibitor 95.95% Unkown
HY-153111 EGFR/HER2-IN-9 Inhibitor 98.73% Unkown
HY-138072 EMI1 Inhibitor 99.78% Unkown
HY-135805B (Rac)-JBJ-04-125-02 acetate / Unkown
HY-150610 EGFR-IN-69 Inhibitor 99.58% Unkown
HY-103442 CGP52411 Inhibitor 99.82% Unkown
HY-15772S1 Osimertinib-13C,d3 99.14% Unkown
HY-13897 CNX-2006 Inhibitor 98.42% Unkown
HY-U00002 ZD-4190 Inhibitor 98.08% Unkown
HY-145960 MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Agonist 99.39% Unkown
HY-126320 EGFR-IN-8 Inhibitor 98.01% Unkown
HY-147413 Unecritinib Inhibitor 98.83% Unkown
HY-147941 MS9427 Degrader 95.29% Unkown
HY-147183 JBJ-09-063 Inhibitor / Unkown
HY-130608 Mutated EGFR-IN-3 Inhibitor / Unkown
HY-135805 JBJ-04-125-02 Inhibitor / Unkown
HY-147219 SIAIS164018 Inhibitor / Unkown
HY-19617A EGFR-IN-1 hydrochloride Inhibitor / Unkown
HY-115716 EGFR-IN-17 Inhibitor 98.42% Unkown
HY-130616 EGFR-IN-11 Inhibitor 99.30% Unkown
HY-50896S Erlotinib-d6 Inhibitor / Unkown
HY-108484 PP 3 Inhibitor 99.79% Unkown
HY-126319 SU5204 Inhibitor 99.46% Unkown
HY-15336 AG 555 Inhibitor ≥98.0% Unkown
HY-149636 Multi-target kinase inhibitor 2 Inhibitor 99.82% Unkown
HY-12806 AG1557 Inhibitor 99.63% Unkown
HY-12872B Nazartinib S-enantiomer 98.66% Unkown
HY-50895S1 Gefitinib-d6 Inhibitor ≥98.0% Unkown
HY-155358 Os30 Inhibitor 98.34% Unkown
HY-144677 pan-HER-IN-2 Inhibitor 98.10% Unkown
HY-13272S2 Dacomitinib-d10 dihydrochloride Inhibitor ≥95.0% Unkown
HY-111452 EGFR-IN-85 Inhibitor / Unkown
HY-118532 Tyrphostin AG30 Inhibitor 99.70% Unkown
HY-101006 Methyl 2,5-dihydroxycinnamate Inhibitor 99.70% Unkown
HY-103441 JNJ28871063 hydrochloride Inhibitor / Unkown
HY-157480 EGFR/AURKB-IN-1 Inhibitor / Unkown
HY-13984 Mutant EGFR inhibitor Inhibitor 99.51% Unkown
HY-157413 YS-67 Inhibitor 99.41% Unkown
HY-B0794 AZ7550 Inhibitor / Unkown
HY-P2503 EGFR Protein Tyrosine Kinase Substrate 99.05% Unkown
HY-100923 H-9 Dihydrochloride Inhibitor / Unkown
HY-103439 GW583340 dihydrochloride Inhibitor / Unkown
HY-133780 Afatinib impurity 11 Inhibitor 99.10% Unkown
HY-138751A limertinib diTFA Inhibitor ≥98.0% Unkown
HY-101756 SDZ281-977 98.00% Unkown
HY-131865 SJF-1521 Degrader 99.20% Unkown
HY-113599 Isoprocurcumenol Activator 95.41% Unkown
HY-19981B Derazantinib dihydrochloride Inhibitor / Unkown
HY-100520 EGFR-IN-2 Inhibitor / Unkown
HY-142283 Dosimertinib Inhibitor / Unkown
HY-18750A Zorifertinib hydrochloride Inhibitor / Unkown
HY-135914 JBJ-02-112-05 Inhibitor / Unkown
HY-132883 EGFR/CSC-IN-1 Inhibitor / Unkown
HY-163428 ZN-A-1041 Inhibitor / Unkown
HY-128860 Mutated EGFR-IN-2 Inhibitor / Unkown
HY-131067 EMI56 Inhibitor 99.72% Unkown
HY-163354 EGFR-IN-103 Inhibitor / Unkown
HY-143734 HER2-IN-6 / Unkown
HY-131066 EMI48 Inhibitor 99.02% Unkown
HY-144048 EGFR-IN-31 / Unkown
HY-10530A Varlitinib tosylate Inhibitor / Unkown
HY-139920A Oritinib mesylate Inhibitor / Unkown
HY-138746 EGFR-IN-15 Inhibitor / Unkown
HY-138627 AST5902 Inhibitor / Unkown
HY-115951 EGFR/HER2-IN-2 Inhibitor / Unkown
HY-125841 EGFR mutant-IN-1 Inhibitor / Unkown
HY-147303 Sacibertinib Inhibitor / Unkown
HY-10407G SU 5402 (GMP) Inhibitor / Unkown
HY-153110 Larotinib Inhibitor / Unkown
HY-111415 EGFR-IN-5 Inhibitor / Unkown
HY-156741 EGFR-IN-87 Inhibitor / Unkown
HY-143733 HER2-IN-5 Inhibitor / Unkown
HY-144053 EGFR-IN-36 Inhibitor / Unkown
HY-50898S3 Lapatinib-d4-1 Inhibitor / Unkown
HY-147802 EGFR-IN-59 Inhibitor / Unkown
HY-142517 EGFR-IN-25 Inhibitor / Unkown
HY-101960 (Z)-Tyrphostin A51 Inhibitor / Unkown
HY-127067 Yuanhuadin Inhibitor / Unkown
HY-156115 EGFR/CDK2-IN-3 Inhibitor / Unkown
HY-146154 EGFR-IN-58 Inhibitor / Unkown
HY-115933 EGFR/BRAF-IN-1 Inhibitor / Unkown
HY-157324 EGFR-IN-94 Inhibitor / Unkown
HY-155227 ALK/EGFR-IN-1 Inhibitor / Unkown
HY-144676 pan-HER-IN-1 Inhibitor / Unkown
HY-156114 EGFR/CDK2-IN-2 Inhibitor / Unkown
HY-151981 EGFR-IN-74 Inhibitor / Unkown
HY-147994 EGFR/HER2-IN-5 Inhibitor / Unkown
HY-153901 PROTAC EGFR degrader 8 Inhibitor / Unkown
HY-151162 HER2-IN-12 Inhibitor / Unkown
HY-110328 PKI-166 hydrochloride Inhibitor / Unkown
HY-161030 EGFR-IN-92 Inhibitor / Unkown
HY-121828 TX-1123 Inhibitor / Unkown
HY-149407 Multi-kinase-IN-4 Inhibitor / Unkown
HY-160613 EGFR/HER2-IN-11 Inhibitor / Unkown
HY-50898S Lapatinib-d4 Inhibitor 99.02% Unkown
HY-163006 EGFR/c-Met-IN-1 Inhibitor / Unkown
HY-150781 EGFR-IN-71 Inhibitor / Unkown
HY-13595R Chrysophanol (Standard) Inhibitor / Unkown
HY-162254 EGFR/ACK1-IN-1 Inhibitor / Unkown
HY-146170 Anticancer agent 69 Inhibitor / Unkown
HY-50898S2 Lapatinib-d5 Inhibitor / Unkown
HY-152019 EGFR/C797S-IN-1 Inhibitor / Unkown
HY-146422 PROTAC EGFR degrader 5 Inhibitor / Unkown
HY-B0794S AZ7550-d5 Inhibitor / Unkown
HY-13272S3 Dacomitinib-d10 Inhibitor / Unkown
HY-162300 EGFR kinase inhibitor 4 Inhibitor / Unkown
HY-144097 HER2-IN-8 Inhibitor / Unkown
HY-144794 EGFR-IN-46 Inhibitor / Unkown
HY-163453 HER2-IN-19 Inhibitor / Unkown
HY-12008S1 Erlotinib-13C6 hydrochloride / Unkown
HY-W008914 (E/Z)-CP-724714 Inhibitor / Unkown
HY-131710 PDE5-IN-3 Inhibitor / Unkown
HY-149518 EGFR/BRAFV600E-IN-3 Inhibitor / Unkown
HY-157994 EGFR WT/T790M-IN-2 Inhibitor / Unkown
HY-112474 Tyrphostin AG 112 Inhibitor 98.55% Unkown
HY-147967 EGFR-IN-63 Inhibitor / Unkown
HY-100663 Gefitinib impurity 2 99.56% Unkown
HY-149517 EGFR/BRAFV600E-IN-2 Inhibitor / Unkown
HY-157399 EGFR/HER2-IN-10 Inhibitor / Unkown
HY-147826 EGFR-IN-60 Inhibitor / Unkown
HY-157402 Topoisomerase II/EGFR-IN-1 / Unkown
HY-153744 JGK-068S Inhibitor / Unkown
HY-158175 EGFR T790M/L858R-IN-4 Inhibitor / Unkown
HY-147862 EGFR-IN-62 Inhibitor / Unkown
HY-147942 MS9449 / Unkown
HY-146472 EGFR-IN-52 Inhibitor / Unkown
HY-155005 EGFR mutant-IN-2 Inhibitor / Unkown
HY-144050 EGFR-IN-33 Inhibitor / Unkown
HY-161126 EGFR-IN-98 Inhibitor / Unkown
HY-144760 EGFR-IN-3 Inducer / Unkown
HY-103437 EGFR-IN-80 Inhibitor / Unkown
HY-143337 EGFR-IN-47 Inhibitor / Unkown
HY-142680 EGFR-IN-23 Inhibitor / Unkown
HY-118998 TX2-121-1 Inhibitor / Unkown
HY-146782 EGFR-IN-49 Inhibitor / Unkown
HY-158153 EGFR-IN-108 Inhibitor / Unkown
HY-151882 EGFR-IN-73 Inhibitor / Unkown
HY-162323 EGFR-IN-106 Inhibitor / Unkown
HY-162062 EGFR WT/T790M/L858R-IN-1 Inhibitor / Unkown
HY-150905 EGFR ligand-2 Inhibitor / Unkown
HY-142512 EGFR-IN-24 Inhibitor / Unkown
HY-163434 PRMT5/EGFR-IN-1 Inhibitor / Unkown
HY-149824 EGFR T790M/L858R-IN-2 Inhibitor 99.66% Unkown
HY-B0793S1 AZ-5104-d2 Inhibitor / Unkown
HY-151159 DHFR-IN-4 Inhibitor / Unkown
HY-10261S1 Afatinib-d4 Inhibitor / Unkown
HY-144052 EGFR-IN-35 Inhibitor / Unkown
HY-142678 EGFR-IN-21 Inhibitor / Unkown
HY-132259 Depatuxizumab mafodotin / Unkown
HY-149530 EGFR-IN-86 Inhibitor / Unkown
HY-142681 EGFR-IN-28 Inhibitor / Unkown
HY-151573 EGFR/CDK2-IN-1 Inhibitor / Unkown
HY-155200 EGFR-IN-84 Inhibitor / Unkown
HY-146239 EGFR/HER2/TS-IN-2 Inhibitor / Unkown
HY-156284 EGFR-IN-89 Inhibitor / Unkown
HY-P5258 Oligopeptide-41 Inducer / Unkown
HY-147992 EGFR/HER2-IN-4 Inhibitor / Unkown
HY-158176 EGFR T790M/L858R-IN-5 Inhibitor / Unkown
HY-161067 EGFR-IN-96 Inhibitor / Unkown
HY-157398 EGFR T790M/L858R-IN-3 Inhibitor / Unkown
HY-145823 EGFR-IN-42 Inhibitor / Unkown
HY-147997 EGFR-IN-68 Inhibitor / Unkown
HY-146132 EGFR-IN-55 Inhibitor / Unkown
HY-146423 PROTAC EGFR degrader 6 Inhibitor / Unkown
HY-101958 Tyrphostin 25 Inhibitor / Unkown
HY-115952 EGFR/HER2-IN-3 Inhibitor / Unkown
HY-108931 AG 1406 Inhibitor 99.03% Unkown
HY-144051 EGFR-IN-34 Inhibitor / Unkown
HY-144056 EGFR-IN-39 Inhibitor / Unkown
HY-143729 EGFR-IN-29 Inhibitor / Unkown
HY-160068 2-2(t) aptamer sodium Chemical / Unkown
HY-155969 EGFR-IN-83 Inhibitor / Unkown
HY-144054 EGFR-IN-37 Inhibitor / Unkown
HY-158154 EGFR-IN-110 Inhibitor / Unkown
HY-142679 EGFR-IN-22 Inhibitor / Unkown
HY-144055 EGFR-IN-38 Inhibitor / Unkown
HY-152144 EGFR-IN-75 Inhibitor / Unkown
HY-151158 EGFR/HER2-IN-7 Inhibitor / Unkown
HY-151377 RET-IN-19 Inhibitor / Unkown
HY-15268 PP487 Inhibitor / Unkown
HY-50898S1 Lapatinib-d7 dihydrochloride Inhibitor / Unkown
HY-155118 EGFR-IN-81 Inhibitor / Unkown
HY-147741 DPPY Inhibitor / Unkown
HY-163419 HER2-IN-18 Inhibitor / Unkown
HY-162099 VEGFR-IN-4 Inhibitor / Unkown
HY-146210 EGFR-IN-50 Inhibitor / Unkown
HY-142283BS N-Desmethyl dosimertinib-d5 / Unkown
HY-144444 NSC381467 Inhibitor / Unkown
HY-146228 HSP90-IN-13 Inhibitor / Unkown
HY-114535 Jaceidin Inhibitor / Unkown
HY-143323 HER2-IN-9 Inhibitor / Unkown
HY-149344 Anticancer agent 133 Inhibitor / Unkown
HY-100064S1 O-Desmethyl gefitinib-d6 Inhibitor / Unkown
HY-157166 EGFR kinase inhibitor 2 Inhibitor / Unkown
HY-149889 EGFR-IN-78 Inhibitor / Unkown
HY-143246 EGFR kinase inhibitor 1 Inhibitor / Unkown
HY-146136 EGFR-IN-56 Inhibitor / Unkown
HY-161031 EGFR-IN-93 Inhibitor / Unkown
HY-151154 EGFR/HER2/DHFR-IN-1 Inhibitor / Unkown
HY-157526 EGFR-TK-IN-1 Inhibitor / Unkown
HY-149846 SIQ17 Inhibitor / Unkown
HY-147798 EGFR/HER2/CDK9-IN-3 Inhibitor / Unkown
HY-162148 HNPMI Inhibitor / Unkown
HY-142519 EGFR-IN-27 Inhibitor / Unkown
HY-147796 EGFR/HER2/CDK9-IN-1 Inhibitor / Unkown
HY-163418 HER2-IN-17 Inhibitor / Unkown
HY-144044 EGFR-IN-30 Inhibitor / Unkown
HY-153557 HER2-IN-13 Inhibitor / Unkown
HY-157912 EGFR-IN-102 Inhibitor / Unkown
HY-141486A PROTAC PARP/EGFR ligand 1 / Unkown
HY-144049 EGFR-IN-32 Inhibitor / Unkown
HY-163371 EGFR WT/T790M-IN-1 Inhibitor / Unkown
HY-P2673 Lys-Arg-Thr-Leu-Arg-Arg / Unkown
HY-149695 EGFR-IN-91 Inhibitor / Unkown
HY-101820A Simotinib hydrochloride Inhibitor / Unkown
HY-149633 EGFR/HER2/DHFR-IN-3 Inhibitor / Unkown
HY-146138 EGFR-IN-57 Inhibitor / Unkown
HY-162332 EGFR-PK/JNK-2-IN-1 Inhibitor / Unkown
HY-161408 GePhos1 / Unkown
HY-161145 EGFR/microtubule-IN-1 Inhibitor / Unkown
HY-137786 EGFR-IN-16 Inhibitor / Unkown
HY-162360 EGFR-IN-109 Inhibitor / Unkown
HY-10261AS Afatinib-d6 dimaleate Inhibitor / Unkown
HY-144605 PROTAC EGFR degrader 3 Inhibitor 97.39% Unkown
HY-163417 HER2-IN-15 Inhibitor / Unkown
HY-156639 EGFR/ErbB-2 inhibitor-1 Inhibitor / Unkown
HY-157432 EGFR-IN-97 Inhibitor / Unkown
HY-163402 EGFR-IN-108 chloride Inhibitor / Unkown
HY-160564 ZNL-0056 Inhibitor / Unkown
HY-145824 EGFR-IN-43 Inhibitor / Unkown
HY-151156 EGFR/HER2-IN-6 Inhibitor / Unkown
HY-19985A (3S,4S)-PF-06459988 99.85% Unkown
HY-147825 EGFR/BRAFV600E-IN-1 Inhibitor / Unkown
HY-145844 EGFR-IN-44 Inhibitor / Unkown
HY-101959 Tyrphostin AG213 Inhibitor / Unkown
HY-147996 EGFR-IN-67 Inhibitor / Unkown
HY-162299 EGFR kinase inhibitor 3 Inhibitor / Unkown
HY-100064S O-Desmethyl gefitinib-d8 Inhibitor 99.84% Unkown
HY-142283CS N-Methyl-dosimertinib-d5 / Unkown
HY-156033 EGFR-IN-88 Inhibitor / Unkown
HY-158178 EGFR T790M/L858R-IN-7 Inhibitor / Unkown
HY-143874 HER2-IN-7 Inhibitor / Unkown
HY-163377 AZ5385 Inhibitor / Unkown
HY-112405 BPIQ-I Inhibitor / Unkown
HY-161269 EGFR-IN-101 Inhibitor / Unkown
HY-161136 EGFR/STAT3-IN-1 Inhibitor / Unkown
HY-P4082 ErbB-2-binding peptide / Unkown
HY-155285 YS-363 Inhibitor / Unkown
HY-144445 NSC114126 Inhibitor / Unkown
HY-155736 MAPK-IN-2 Inhibitor / Unkown
HY-163420 HER2-IN-16 Inhibitor / Unkown
HY-147995 EGFR-IN-64 Inhibitor / Unkown
HY-146474 EGFR-IN-54 Inhibitor / Unkown
HY-146349 PROTAC EGFR degrader 4 Inhibitor / Unkown
HY-18213 EGFR-IN-9 Inhibitor 98.84% Unkown
HY-155178 Antiproliferative agent-34 Inhibitor / Unkown
HY-W423595 BEBT-109 Inhibitor / Unkown
HY-10261E (R)-Afatinib Inhibitor / Unkown
HY-146238 EGFR/HER2/TS-IN-1 Inhibitor / Unkown
HY-149632 EGFR/HER2/DHFR-IN-2 Inhibitor / Unkown
HY-163094 EGFR-IN-95 Inhibitor / Unkown
HY-149401 EGFR-IN-82 Inhibitor / Unkown
HY-141640 MS154 Inhibitor / Unkown
HY-152098 HX103 Inhibitor / Unkown
HY-161275 BI-4732 Inhibitor / Unkown
HY-113549 Erbstatin Inhibitor / Unkown
HY-153557A HER2-IN-14 Inhibitor / Unkown
HY-156470 Multi-kinase-IN-6 Inhibitor / Unkown
HY-139884 EGFR-IN-18 Inhibitor / Unkown
HY-W174279 Tyrphostin 8 Inhibitor ≥98.0% Unkown
HY-161045 T-1-DOCA Inhibitor / Unkown
HY-161320 EGFR-IN-105 Inhibitor / Unkown
HY-143445 EGFR-IN-48 Inhibitor / Unkown
HY-145867 EGFR-IN-45 Inhibitor / Unkown
HY-160682 EGFR/HER2-IN-12 Inhibitor / Unkown
HY-137028 2′-Thioadenosine Inhibitor / Unkown
HY-143901 EGFR-IN-40 Inhibitor / Unkown
HY-161146 EGFR-IN-100 Inhibitor / Unkown
HY-146473 EGFR-IN-53 Inhibitor / Unkown
HY-146471 EGFR-IN-51 Inhibitor / Unkown
HY-156457 EGFR-IN-90 Inhibitor / Unkown
HY-147860 EGFR-IN-61 Inhibitor / Unkown
HY-13524A AG-1478 hydrochloride Inhibitor / Unkown
HY-P1085 Epidermal Growth Factor Receptor Peptide (985-996) Chemical / Unkown
HY-156116 EGFR/CDK2-IN-4 Inhibitor / Unkown
HY-151161 EGFR/HER2-IN-8 Inhibitor / Unkown
HY-149556 MTX-241F Inhibitor / Unkown
HY-108016 Peruvoside Inhibitor / Unkown
HY-131864 SJF-1528 Degrader / Unkown
HY-161319 EGFR-IN-104 Inhibitor / Unkown
HY-148460 Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine Inhibitor / Unkown
HY-158018 EGFR-TK-IN-2 Inhibitor / Unkown
HY-147797 EGFR/HER2/CDK9-IN-2 Inhibitor / Unkown
HY-149275 PKM2/PDK1-IN-1 Inhibitor / Unkown
HY-158177 EGFR T790M/L858R-IN-6 Inhibitor / Unkown
HY-101522 CHMFL-EGFR-202 Inhibitor 99.75% Unkown
HY-147858 PROTAC EGFR degrader 7 Inhibitor / Unkown
HY-50896S1 Erlotinib-13C6 Inhibitor / Unkown
HY-150782 UNC-CA359 Inhibitor / Unkown
HY-158016 Antiproliferative agent-49 Inhibitor / Unkown
HY-100636A Gefitinib N-oxide hydrochloride Inhibitor / Unkown
HY-155074 EGFR-IN-79 Inhibitor / Unkown
HY-156912 Tyrosine kinase-IN-7 Inhibitor 99.25% Unkown
HY-158149 T-1-PMPA Inhibitor / Unkown
HY-P2548 pp60 (v-SRC) Autophosphorylation Site, Phosphorylated / Unkown
HY-144441 NSC81111 Inhibitor / Unkown
HY-15769A WHI-P180 hydrochloride Inhibitor / Unkown
HY-157579 MS154N / Unkown
HY-163396 EGFR-IN-107 Inhibitor / Unkown
HY-137433A Befotertinib mesylate Inhibitor / Unkown
HY-117523 (Z)-RG-13022 Inhibitor / Unkown
HY-157581 MS39 Degrader / Unkown
HY-50895S2 Gefitinib-d3 Inhibitor / Unkown
HY-32721S Neratinib-d6 Inhibitor / Unkown
HY-123766 EGFR-IN-99 Inhibitor / Unkown
HY-18957B Lifirafenib maleate Inhibitor / Unkown
HY-15375 Allitinib Inhibitor / Unkown
HY-146262 LDC0496 Inhibitor / Unkown
Inhibitory Antibodies (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9912A Pertuzumab (PBS) Inhibitor 99.10% Unkown
HY-P99684 Laprituximab Inhibitor 95.00% Unkown
HY-P99892 Serclutamab 99.97% Unkown
HY-P99888 Pimurutamab / Unkown
HY-P99324 Tomuzotuximab Inhibitor / Unkown
HY-P99558 Timigutuzumab Inhibitor / Unkown
HY-P990055 Nezutatug Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Egfr NCBI NCBI:1956
Canis familiaris Egfr NCBI NCBI:404306
Macaca fascicularis Egfr NCBI NCBI:102138724
Rattus norvegicus Egfr NCBI NCBI:24329
Macaca mulatta Egfr NCBI NCBI:613027