ASB5 - ankyrin repeat and SOCS box containing 5 Gene

Homo sapiens

Also known as ASB-5

Gene ID: 140458 | Gene type: protein coding

About ASB5

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,213,673-176,277,524 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues and 2 paralogues. Biased expression in prostate (RPKM 5.3), urinary bladder (RPKM 4.0) and 6 other tissues.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008]

ASB5 Products(2)

mRNA	Protein	Name
NM_001410863.1	NP_001397792.1	ankyrin repeat and SOCS box protein 5 isoform 2
NM_080874.4	NP_543150.1	ankyrin repeat and SOCS box protein 5 isoform 1

ASB5 Protein Structure

Ank_2

SOCS_box

0
100
200
300
329 a.a.

Protein Preferred Names

Protein Names

ankyrin repeat and SOCS box protein 5

SOCS box protein ASB-5

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01070	ASB5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ASB5	VGNC	VGNC:59961
Rattus norvegicus	ASB5	RGD	RGD:1565973
Canis familiaris	ASB5	VGNC	VGNC:38165
Bos taurus	ASB5	VGNC	VGNC:26198
Mus musculus	ASB5	MGD	MGI:1923544
Macaca mulatta	ASB5	VGNC	VGNC:69849