1. Gene
  2. CSRP2 - cysteine and glycine rich protein 2 Gene

CSRP2 - cysteine and glycine rich protein 2 Gene

Homo sapiens

Also known as CRP2; LMO5; SmLIM

Gene ID: 1466 | Gene type: protein coding

About CSRP2

Cytogenetic location: 12q21.2 Genomic coordinates (GRCh38): 12:76,858,709-76,879,019 (from NCBI)

This gene has 7 transcripts (splice variants), 217 orthologues and 2 paralogues. Ubiquitous expression in esophagus (RPKM 37.2), placenta (RPKM 35.3) and 23 other tissues.

Summary

CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

CSRP2 Products(9)

mRNA Protein Name
NM_001300965.2 NP_001287894.1 cysteine and glycine-rich protein 2 isoform b
NM_001321.3 NP_001312.1 cysteine and glycine-rich protein 2 isoform b
NM_001413535.1 NP_001400464.1 cysteine and glycine-rich protein 2 isoform b
NM_001413537.1 NP_001400466.1 cysteine and glycine-rich protein 2 isoform b
NM_001413538.1 NP_001400467.1 cysteine and glycine-rich protein 2 isoform b
NM_001413539.1 NP_001400468.1 cysteine and glycine-rich protein 2 isoform a
NM_001413540.1 NP_001400469.1 cysteine and glycine-rich protein 2 isoform c
NM_001413541.1 NP_001400470.1 cysteine and glycine-rich protein 2 isoform d
NM_001413542.1 NP_001400471.1 cysteine and glycine-rich protein 2 isoform e

CSRP2 Protein Structure

LIM

LIM: LIM domain (10 - 65)

LIM

LIM: LIM domain (119 - 175)

  • 0
  • 100
  • 193 a.a.
Protein Preferred Names Protein Names

cysteine and glycine-rich protein 2

LIM domain only 5, smooth muscle

Related Diseases

Diseases Alias
Chromosome 8q21.11 Deletion Syndrome

8q21.11 Microdeletion Syndrome

Del(8)(Q21.11)

Deletion 8q21.11

Monosomy 8q21.11

Fanconi Anemia, Complementation Group C

Fanconi Anemia Complementation Group C

FANCC

Facc

Fac

Fa3

Fanconi Pancytopenia Type 3

Fanconi Pancytopenia, Type 3

Faces Syndrome

Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies

Friedman-Goodman Syndrome

Abnormality Of The Face

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Macaca mulatta CSRP2 VGNC VGNC:71528
Rattus norvegicus CSRP2 RGD RGD:61950
Bos taurus CSRP2 VGNC VGNC:27774
Felis catus CSRP2 VGNC VGNC:83862
Mus musculus CSRP2 MGD MGI:1202907