2. Gene
  3. PPP1R1C - protein phosphatase 1 regulatory inhibitor subunit 1C Gene

PPP1R1C - protein phosphatase 1 regulatory inhibitor subunit 1C Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IPP5

Gene ID: 151242 | Gene type: protein coding

About PPP1R1C

Cytogenetic location: 2q31.3-q32.1 Genomic coordinates (GRCh38): 2:181,954,480-182,131,385 (from NCBI)

This gene has 13 transcripts (splice variants), 187 orthologues and 2 paralogues. Biased expression in heart (RPKM 4.6), testis (RPKM 4.4) and 5 other tissues.

Summary

Protein phosphatase-1 (PP1) is a major serine/threonine Phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]

PPP1R1C Products(3)

mRNA Protein Name
NM_001080545.3 NP_001074014.1 protein phosphatase 1 regulatory subunit 1C isoform 2
NM_001261424.2 NP_001248353.1 protein phosphatase 1 regulatory subunit 1C isoform 1
NM_001261425.2 NP_001248354.1 protein phosphatase 1 regulatory subunit 1C isoform 2

PPP1R1C Protein Structure

DARPP-32

DARPP-32: Protein phosphatase inhibitor 1/DARPP-32 (1 - 105)

  • 0
  • 100
  • 109 a.a.
Protein Preferred Names Protein Names

protein phosphatase 1 regulatory subunit 1C

PP1 inhibitor protein 5

Related Diseases

Diseases Alias
Conduct Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10994 PPP1R1C Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PPP1R1C VGNC VGNC:33235
Canis familiaris PPP1R1C VGNC VGNC:44888
Felis catus PPP1R1C VGNC VGNC:80317
Macaca mulatta PPP1R1C VGNC VGNC:76256
Mus musculus PPP1R1C MGD MGI:1923185
Rattus norvegicus PPP1R1C RGD RGD:1562095