SDE2 - SDE2 telomere maintenance homolog Gene

Homo sapiens

Also known as C1orf55; dJ671D7.1

Gene ID: 163859 | Gene type: protein coding

About SDE2

This gene has 1 transcript (splice variant), 199 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 11.6), thyroid (RPKM 7.7) and 25 other tissues.

Summary

Enables damaged DNA binding activity. Involved in several processes, including cellular response to UV; mitotic G1 DNA damage checkpoint signaling; and protein ubiquitination. Located in several cellular components, including Golgi apparatus; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

SDE2 Products(1)

mRNA	Protein	Name
NM_152608.4	NP_689821.3	replication stress response regulator SDE2

SDE2 Protein Structure

Telomere_Sde2

Telomere_Sde2_2

0
100
200
300
400
451 a.a.

Protein Preferred Names

Protein Names

replication stress response regulator SDE2

UPF0667 protein C1orf55

Related Diseases

Diseases

Alias

Meningeal Melanomatosis

Leptomeningeal Melanomatosis

Meningeal Melanoma

Melanoma Of The Leptomeninges

Leptomeningeal Melanoma

Malignant Leptomeningeal Tumor

Malignant Leptomeningeal Tumour	Malignant Tumor Of Leptomeninges
Malignant Tumour Of Leptomeninges	Malignant Leptomeningeal Neoplasm

Junctional Epidermolysis Bullosa

Epidermolysis Bullosa, Junctional	Jeb
Epidermolysis Bullosa Atrophicans	Congenital Junctional Epidermolysis Bullosa
Epidermolysis Bullosa Junctional	Junctional Eb - [Epidermolysis Bullosa]
Jeb - [Junctional Epidermolysis Bullosa]	Lucidolytic Epidermolysis Bullosa

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12586	SDE2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SDE2	VGNC	VGNC:100135
Bos taurus	SDE2	VGNC	VGNC:34384
Mus musculus	SDE2	MGD	MGI:2384788
Felis catus	SDE2	VGNC	VGNC:64948
Rattus norvegicus	SDE2	RGD	RGD:1305572
Canis familiaris	SDE2	VGNC	VGNC:45946