1. Gene
  2. Junb - jun B proto-oncogene Gene

Junb - jun B proto-oncogene Gene

Mus musculus
Gene ID: 16477 | Gene type: protein coding

About Junb

Chromosome 8: 85,701,113-85,705,347 reverse strand.GRCm39:CM001001.3

This gene has 2 transcripts (splice variants), 236 orthologues, 2 paralogues and is associated with 20 phenotypes.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including decidualization; embryo development; and osteoblast proliferation. Predicted to be located in nucleoplasm. Predicted to be part of transcription factor AP-1 complex. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and hemolymphoid system gland. Used to study systemic lupus erythematosus. Orthologous to human JUNB (JunB proto-oncogene, AP-1 transcription factor subunit). [provided by Alliance of Genome Resources, Apr 2022]

Junb Products(1)

mRNA Protein Name
NM_008416.3 NP_032442.1 transcription factor JunB

Junb Protein Structure

Jun

Jun: pfam03957 (5 - 252)

bZIP_Jun

bZIP_Jun: cd14696 (266 - 325)

bZIP_Jun

bZIP_Jun: cd14696 (267 - 318)

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  • 344 a.a.
Protein Preferred Names Protein Names

transcription factor JunB

Jun-B oncogene

myD21

transcription factor AP-1 subunit JunB

transcription factor jun-B

Orthologs Information

Species Symbol Source ID
Homo sapiens Junb NCBI NCBI:3726