SGK3 - serum/glucocorticoid regulated kinase family, member 3 Gene

Rattus norvegicus

Also known as Cisk; Sgkl

Gene ID: 171498 | Gene type: protein coding

About SGK3

Primary_assembly 5: 9,346,040-9,415,476 reverse strand.mRatBN7.2:CM026978.1

This gene has 1 transcript (splice variant), 212 orthologues, 13 paralogues and is associated with 2 phenotypes. Biased expression in Spleen (RPKM 13.9), Thymus (RPKM 9.3) and 9 other tissues.

Summary

Predicted to enable Potassium Channel regulator activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in cytoplasmic vesicle and nucleoplasm. Orthologous to several human genes including C8orf44-SGK3 (C8orf44-SGK3 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

SGK3 Products(1)

mRNA	Protein	Name
NM_001376043.1	NP_001362972.1	serine/threonine-protein kinase Sgk3

SGK3 Protein Structure

PX_CISK

STKc_SGK3

0
100
200
300
400
496 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase Sgk3

cytokine-independent survival kinase

serum/glucocorticoid-regulated kinase 3

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125878	PROTAC SGK3 degrader-1	Inhibitor	99.02%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	SGK3	NCBI	NCBI:23678