Ptgir - prostaglandin I receptor (IP) Gene

Mus musculus

Also known as IP; PGI2

Gene ID: 19222 | Gene type: protein coding

About Ptgir

Chromosome 7: 16,640,415-16,644,830 forward strand.GRCm39:CM001000.3

This gene has 2 transcripts (splice variants), 187 orthologues, 7 paralogues and is associated with 11 phenotypes. Broad expression in mammary gland adult (RPKM 4.9), spleen adult (RPKM 4.5) and 19 other tissues.

Summary

Predicted to enable prostacyclin receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of platelet-derived growth factor receptor signaling pathway; and negative regulation of smooth muscle cell proliferation. Acts upstream of or within response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; gallbladder; genitourinary system; hemolymphoid system gland; and limb segment. Orthologous to human PTGIR (prostaglandin I2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgir Products(1)

mRNA	Protein	Name
NM_008967.3	NP_032993.2	prostacyclin receptor

Ptgir Protein Structure

7tm_GPCRs

0
100
200
300
415 a.a.

Protein Preferred Names

Protein Names

prostacyclin receptor

PGI receptor	PGI2 receptor
prostaglandin I2 receptor	prostanoid IP receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11386	PTGIR Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11387	Ptgir Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11388	Ptgir Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ptgir	NCBI	NCBI:5739

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