2. Gene
  3. METTL15 - methyltransferase like 15 Gene

METTL15 - methyltransferase like 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as METT5D1

Gene ID: 196074 | Gene type: protein coding

About METTL15

Cytogenetic location: 11p14.1 Genomic coordinates (GRCh38): 11:28,108,388-28,532,475 (from NCBI)

This gene has 12 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in thyroid (RPKM 2.9), adrenal (RPKM 2.8) and 25 other tissues.

Summary

Predicted to enable rRNA (cytosine-N4-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Predicted to be located in mitochondrial matrix. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

METTL15 Products(3)

mRNA Protein Name
NM_001113528.2 NP_001107000.1 12S rRNA N4-methylcytidine (m4C) methyltransferase isoform 1
NM_001297775.2 NP_001284704.1 12S rRNA N4-methylcytidine (m4C) methyltransferase isoform 3
NM_152636.3 NP_689849.2 12S rRNA N4-methylcytidine (m4C) methyltransferase isoform 2

METTL15 Protein Structure

Methyltransf_5

Methyltransf_5: MraW methylase family (71 - 405)

  • 0
  • 100
  • 200
  • 300
  • 407 a.a.
Protein Preferred Names Protein Names

12S rRNA N4-methylcytidine (m4C) methyltransferase

12S rRNA m4C methyltransferase

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08356 METTL15 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris METTL15 VGNC VGNC:52267
Bos taurus METTL15 VGNC VGNC:54885
Rattus norvegicus METTL15 RGD RGD:1304978
Felis catus METTL15 VGNC VGNC:82018
Mus musculus METTL15 MGD MGI:1924144
Macaca mulatta METTL15 VGNC VGNC:101350