EMP3 - epithelial membrane protein 3 Gene

Homo sapiens

Also known as YMP

Gene ID: 2014 | Gene type: protein coding

About EMP3

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,325,552-48,330,553 (from NCBI)

This gene has 9 transcripts (splice variants), 239 orthologues and 10 paralogues. Ubiquitous expression in bone marrow (RPKM 63.7), appendix (RPKM 40.0) and 24 other tissues.

Summary

The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

EMP3 Products(2)

mRNA	Protein	Name
NM_001313905.1	NP_001300834.1	epithelial membrane protein 3
NM_001425.3	NP_001416.1	epithelial membrane protein 3

EMP3 Protein Structure

PMP22_Claudin

0
100
163 a.a.

Protein Preferred Names

Protein Names

epithelial membrane protein 3

EMP-3

Related Diseases

Diseases

Alias

Adult Oligodendroglioma

Adult Brain Oligodendroglioma	Grade Ii Adult Oligodendroglial Tumor
Oligodendroglioma, Adult

Charcot-Marie-Tooth Disease

Cmt	Hmsn
Hereditary Motor And Sensory Neuropathy	Pma
Cmt - Charcot-Marie-Tooth Disease	Charcot Marie Tooth Disease
Charcot-Marie-Tooth Hereditary Neuropathy	Charcot-Marie-Tooth Syndrome
Peroneal Muscular Atrophy	Hereditary Motor And Sensory Neuropathies

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04361	EMP3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	EMP3	VGNC	VGNC:40354
Bos taurus	EMP3	VGNC	VGNC:28483
Macaca mulatta	EMP3	VGNC	VGNC:72215
Mus musculus	EMP3	MGD	MGI:1098729
Rattus norvegicus	EMP3	RGD	RGD:621094