1. Gene
  2. RNF152 - ring finger protein 152 Gene

RNF152 - ring finger protein 152 Gene

Homo sapiens
Gene ID: 220441 | Gene type: protein coding

About RNF152

Cytogenetic location: 18q21.33 Genomic coordinates (GRCh38): 18:61,808,067-61,894,412 (from NCBI)

This gene has 5 transcripts (splice variants), 207 orthologues and 12 paralogues. Biased expression in kidney (RPKM 29.4), liver (RPKM 4.9) and 13 other tissues.

Summary

Enables small GTPase binding activity and ubiquitin protein ligase activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of TORC1 signaling; and protein polyubiquitination. Located in lysosomal membrane. Is integral component of organelle membrane. [provided by Alliance of Genome Resources, Apr 2022]

RNF152 Products(1)

mRNA Protein Name
NM_173557.3 NP_775828.1 E3 ubiquitin-protein ligase RNF152

RNF152 Protein Structure

zf-RING_5

zf-RING_5: zinc-RING finger domain (11 - 55)

  • 0
  • 100
  • 203 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase RNF152

RING-type E3 ubiquitin transferase RNF152

Orthologs Information

Species Symbol Source ID
Macaca mulatta RNF152 VGNC VGNC:104245
Rattus norvegicus RNF152 RGD RGD:1305251
Canis familiaris RNF152 VGNC VGNC:45641
Bos taurus RNF152 VGNC VGNC:106897
Mus musculus RNF152 MGD MGI:2443787
Felis catus RNF152 VGNC VGNC:64676